Paul Meraner
Overview
Explore the profile of Paul Meraner including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
1246
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0
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Recent Articles
1.
Meraner P, Avetisyan A, Swift K, Cheng Y, Barria R, Freeman M
bioRxiv
. 2025 Jan;
PMID: 39868134
Competing Interests: Marc Freeman is co-founder of Nura Bio, a biotech startup pursuing novel neuroprotective therapies including SARM1 inhibition. The remaining authors declare no competing interests.
2.
Kriegsman B, Vangala P, Chen B, Meraner P, Brass A, Garber M, et al.
J Immunol
. 2019 Sep;
203(7):1999-2010.
PMID: 31471524
To arise and progress, cancers need to evade immune elimination. Consequently, progressing tumors are often MHC class I (MHC-I) low and express immune inhibitory molecules, such as PD-L1, which allows...
3.
E X, Meraner P, Lu P, Perreira J, Aker A, McDougall W, et al.
Proc Natl Acad Sci U S A
. 2019 Mar;
116(14):7043-7052.
PMID: 30894498
A human cytomegalovirus (HCMV) pentameric glycoprotein complex (PC), gH-gL-UL128-UL130-UL131A, is necessary for viral infection of clinically relevant cell types, including epithelial cells, which are important for interhost transmission and disease....
4.
Bazzone L, King M, MacKay C, Kyawe P, Meraner P, Lindstrom D, et al.
mBio
. 2019 Feb;
10(1).
PMID: 30723129
Encephalomyocarditis virus (EMCV) is a picornavirus that produces lytic infections in murine and human cells. Employing a genome-wide CRISPR-Cas9 knockout screen to find host factors required for EMCV infection, we...
5.
Suddala K, Lee C, Meraner P, Marin M, Markosyan R, Desai T, et al.
PLoS Pathog
. 2019 Jan;
15(1):e1007532.
PMID: 30640957
Late endosome-resident interferon-induced transmembrane protein 3 (IFITM3) inhibits fusion of diverse viruses, including Influenza A virus (IAV), by a poorly understood mechanism. Despite the broad antiviral activity of IFITM3, viruses...
6.
Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, et al.
Nature
. 2016 Sep;
538(7625):350-355.
PMID: 27680706
Clostridium difficile toxin B (TcdB) is a critical virulence factor that causes diseases associated with C. difficile infection. Here we carried out CRISPR-Cas9-mediated genome-wide screens and identified the members of...
7.
Savidis G, McDougall W, Meraner P, Perreira J, Portmann J, Trincucci G, et al.
Cell Rep
. 2016 Jun;
16(1):232-246.
PMID: 27342126
The flaviviruses dengue virus (DENV) and Zika virus (ZIKV) are severe health threats with rapidly expanding ranges. To identify the host cell dependencies of DENV and ZIKV, we completed orthologous...
8.
Savidis G, Perreira J, Portmann J, Meraner P, Guo Z, Green S, et al.
Cell Rep
. 2016 Jun;
15(11):2323-30.
PMID: 27268505
Zika virus has emerged as a severe health threat with a rapidly expanding range. The IFITM family of restriction factors inhibits the replication of a broad range of viruses, including...
9.
Perreira J, Meraner P, Brass A
Adv Virus Res
. 2016 Mar;
94:1-51.
PMID: 26997589
Over the last several years a wealth of transformative human-virus interaction discoveries have been produced using loss-of-function functional genomics. These insights have greatly expanded our understanding of how human pathogenic...
10.
Perreira J, Aker A, Savidis G, Chin C, McDougall W, Portmann J, et al.
Cell Rep
. 2015 Jul;
12(5):850-63.
PMID: 26212330
Human rhinovirus (HRV) causes upper respiratory infections and asthma exacerbations. We screened multiple orthologous RNAi reagents and identified host proteins that modulate HRV replication. Here, we show that RNASEK, a...