Aaron M Aker
Overview
Explore the profile of Aaron M Aker including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
655
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Recent Articles
1.
E X, Meraner P, Lu P, Perreira J, Aker A, McDougall W, et al.
Proc Natl Acad Sci U S A
. 2019 Mar;
116(14):7043-7052.
PMID: 30894498
A human cytomegalovirus (HCMV) pentameric glycoprotein complex (PC), gH-gL-UL128-UL130-UL131A, is necessary for viral infection of clinically relevant cell types, including epithelial cells, which are important for interhost transmission and disease....
2.
Savidis G, McDougall W, Meraner P, Perreira J, Portmann J, Trincucci G, et al.
Cell Rep
. 2016 Jun;
16(1):232-246.
PMID: 27342126
The flaviviruses dengue virus (DENV) and Zika virus (ZIKV) are severe health threats with rapidly expanding ranges. To identify the host cell dependencies of DENV and ZIKV, we completed orthologous...
3.
Chin C, Perreira J, Savidis G, Portmann J, Aker A, Feeley E, et al.
Cell Rep
. 2015 Nov;
13(8):1717-31.
PMID: 26586435
Direct visualization of HIV-1 replication would improve our understanding of the viral life cycle. We adapted established technology and reagents to develop an imaging approach, ViewHIV, which allows evaluation of...
4.
Perreira J, Aker A, Savidis G, Chin C, McDougall W, Portmann J, et al.
Cell Rep
. 2015 Jul;
12(5):850-63.
PMID: 26212330
Human rhinovirus (HRV) causes upper respiratory infections and asthma exacerbations. We screened multiple orthologous RNAi reagents and identified host proteins that modulate HRV replication. Here, we show that RNASEK, a...
5.
Lin T, Chin C, Everitt A, Clare S, Perreira J, Savidis G, et al.
Cell Rep
. 2013 Nov;
5(4):895-908.
PMID: 24268777
The IFITMs inhibit influenza A virus (IAV) replication in vitro and in vivo. Here, we establish that the antimycotic heptaen, amphotericin B (AmphoB), prevents IFITM3-mediated restriction of IAV, thereby increasing...
6.
John S, Chin C, Perreira J, Feeley E, Aker A, Savidis G, et al.
J Virol
. 2013 May;
87(14):7837-52.
PMID: 23658454
The interferon-induced transmembrane protein 3 (IFITM3) gene is an interferon-stimulated gene that inhibits the replication of multiple pathogenic viruses in vitro and in vivo. IFITM3 is a member of a...