Paul M Brennan
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Explore the profile of Paul M Brennan including associated specialties, affiliations and a list of published articles.
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125
Citations
2423
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Recent Articles
11.
Al Shboul S, Boyle S, Singh A, Saleh T, Alrjoub M, Abu Al Karsaneh O, et al.
Brain Tumor Pathol
. 2023 Dec;
41(1):4-17.
PMID: 38097874
Deletion of CDKN2A occurs in 50% of glioblastomas (GBM), and IFNA locus deletion in 25%. These genes reside closely on chromosome 9. We investigated whether CDKN2A and IFNA were co-deleted...
12.
Poon M, Brennan P, Jin K, Sudlow C, Figueroa J
BMC Med
. 2023 Nov;
21(1):431.
PMID: 37953241
Background: Elevated standardised mortality ratio of cardiovascular diseases (CVD) in patients with brain tumours may result from differences in the CVD incidences and cardiovascular risk factors. We compared the risk...
13.
Cameron J, Sala A, Antoniou G, Brennan P, Butler H, Conn J, et al.
Br J Cancer
. 2023 Sep;
129(10):1658-1666.
PMID: 37717120
Background: A rapid, low-cost blood test that can be applied to reliably detect multiple different cancer types would be transformational. Methods: In this large-scale discovery study (n = 2092 patients)...
14.
ODowd E, Merriel S, Cheng V, Khan S, Howells L, Gopal D, et al.
BMC Cancer
. 2023 Sep;
23(1):820.
PMID: 37667231
Background: Global annual cancer incidence is forecast to rise to 27.5 M by 2040, a 62% increase from 2018. For most cancers, prevention and early detection are the most effective...
15.
Tzioras M, Daniels M, Davies C, Baxter P, King D, McKay S, et al.
Cell Rep Med
. 2023 Aug;
4(9):101175.
PMID: 37652017
Synapse loss correlates with cognitive decline in Alzheimer's disease (AD). Data from mouse models suggests microglia are important for synapse degeneration, but direct human evidence for any glial involvement in...
16.
Sala A, Cameron J, Brennan P, Crosbie E, Curran T, Gray E, et al.
J Exp Clin Cancer Res
. 2023 Aug;
42(1):207.
PMID: 37580713
The advances in cancer research achieved in the last 50 years have been remarkable and have provided a deeper knowledge of this disease in many of its conceptual and biochemical...
17.
Keenlyside A, Rae B, Brennan P, Hughes M
Surgeon
. 2023 Jul;
21(6):e352-e360.
PMID: 37468362
Background: Exposure to stress prior to or during surgery can negatively impact performance. Management of stress is an essential non-technical skill required for safe practice. The effects of exposure to...
18.
Desborough M, Salman R, Stanworth S, Havard D, Woodhouse L, Craig J, et al.
Lancet Neurol
. 2023 Jun;
22(7):557-567.
PMID: 37353276
Background: The risk of death from spontaneous intracerebral haemorrhage is increased for people taking antiplatelet drugs. We aimed to assess the feasibility of randomising patients on antiplatelet drug therapy with...
19.
Brennan P, Hernandez Martinez J, Reed M, Shenkin S
BMJ
. 2023 Jun;
381:e072956.
PMID: 37268308
No abstract available.
20.
Brennan J, Poon M, Christopher E, Fulton O, Porteous C, Brennan P
Trials
. 2023 May;
24(1):370.
PMID: 37259102
Background: Patient and public involvement (PPI) in clinical trial design contributes to ensuring the research objectives and outcome measures are relevant to patients. The minimal clinically important difference (MCID) in...