Paul L Skipper
Overview
Explore the profile of Paul L Skipper including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
30
Citations
465
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ravindra K, Trudel L, Wishnok J, Wogan G, Tannenbaum S, Skipper P
ACS Chem Biol
. 2016 Feb;
11(5):1230-7.
PMID: 26866676
Monocyclic aromatic amines are widespread environmental contaminants with multiple sources such as combustion products, pharmaceuticals, and pesticides. Their phenolic metabolites are converted intracellularly to electrophilic quinone imines upon autoxidation and...
2.
Chao M, Erkekoglu P, Tseng C, Ye W, Trudel L, Skipper P, et al.
J Appl Toxicol
. 2014 Sep;
35(5):466-77.
PMID: 25178734
Exposure to monocyclic aromatic alkylanilines (MAAs), namely 2,6-dimethylaniline (2,6-DMA), 3,5-dimethylaniline (3,5-DMA) and 3-ethylaniline (3-EA), was significantly and independently associated with bladder cancer incidence. 3,5-DMAP (3,5-dimethylaminophenol), a metabolite of 3,5-DMA, was...
3.
Erkekoglu P, Chao M, Ye W, Ge J, Trudel L, Skipper P, et al.
Food Chem Toxicol
. 2014 Jul;
72:98-110.
PMID: 25014158
Most common alkylanilines in the environment are 2,6-dimethylaniline (2,6-DMA), 3,5-dimethylaniline (3,5-DMA), and 3-ethylaniline (3-EA). 3,5-Dimethylaminophenol (3,5-DMAP), a metabolite of 3,5-DMA, is of particular interest, as it is potentially genotoxic. Supplementation...
4.
Chao M, Erkekoglu P, Tseng C, Ye W, Trudel L, Skipper P, et al.
Toxicol Sci
. 2014 Jun;
141(1):300-13.
PMID: 24973092
Epidemiological studies have demonstrated extensive human exposure to the monocyclic aromatic amines, particularly to 3,5-dimethylaniline, and found an association between exposure to these compounds and risk for bladder cancer. Little...
5.
Louissaint N, Cao Y, Skipper P, Liberman R, Tannenbaum S, Nimmagadda S, et al.
AIDS Res Hum Retroviruses
. 2013 Apr;
29(11):1443-50.
PMID: 23600365
HIV seroconversion outcomes in preexposure prophylaxis (PrEP) trials of oral tenofovir (TFV)-containing regimens are highly sensitive to drug concentration, yet less-than-daily dosing regimens are under study. Description of TFV and...
6.
Ye W, Seneviratne U, Chao M, Ravindra K, Wogan G, Tannenbaum S, et al.
Chem Res Toxicol
. 2012 Dec;
25(12):2627-9.
PMID: 23194336
Aminophenols can redox cycle through the corresponding quinone imines to generate ROS. The electrophilic quinone imine intermediate can react with protein thiols as a mechanism of immobilization in vivo. Here,...
7.
Chen J, Flexner C, Liberman R, Skipper P, Louissaint N, Tannenbaum S, et al.
J Acquir Immune Defic Syndr
. 2012 Nov;
61(5):593-9.
PMID: 23187888
Objective: Phase 0 studies can provide initial pharmacokinetics (PKs) data in humans and help to facilitate early drug development, but their predictive value for standard dosing is controversial. To evaluate...
8.
Chao M, Kim M, Ye W, Ge J, Trudel L, Belanger C, et al.
Toxicol Sci
. 2012 Jul;
130(1):48-59.
PMID: 22831970
Several alkylanilines with structures more complex than toluidines have been associated epidemiologically with human cancer. Their mechanism of action remains largely undetermined, and there is no reported evidence that it...
9.
Watzek N, Bohm N, Feld J, Scherbl D, Berger F, Merz K, et al.
Chem Res Toxicol
. 2012 Jan;
25(2):381-90.
PMID: 22211389
Acrylamide (AA) is formed during the heating of food and is classified as a genotoxic carcinogen. The margin of exposure (MOE), representing the distance between the bench mark dose associated...
10.
Turesky R, Bessette E, Dunbar D, Liberman R, Skipper P
Chem Res Toxicol
. 2011 Nov;
25(2):410-21.
PMID: 22118226
2-Amino-1,7-dimethylimidazo[4,5-g]quinoxaline (MeIgQx) is a recently discovered heterocyclic aromatic amine (HAA) that is formed during the cooking of meats. MeIgQx is an isomer of 2-amino-3,8-dimethylmidazo[4,5-f]quinoxaline (MeIQx), a rodent carcinogen and possible...