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Paul Krzyzanowski

Explore the profile of Paul Krzyzanowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 542
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Recent Articles
1.
Aynaud M, Caldwell L, Al-Zahrani K, Barutcu S, Chan K, Obersterescu A, et al.
Nat Commun . 2024 Dec; 15(1):10795. PMID: 39738001
Highly mutable pathogens generate viral diversity that impacts virulence, transmissibility, treatment, and thwarts acquired immunity. We previously described C19-SPAR-Seq, a high-throughput, next-generation sequencing platform to detect SARS-CoV-2 that we here...
2.
Egyud M, Tejani M, Pennathur A, Luketich J, Sridhar P, Yamada E, et al.
Ann Thorac Surg . 2019 May; 108(2):343-349. PMID: 31059681
Background: Recent literature has demonstrated the potential of "liquid biopsy" and detection of circulating tumor (ct)DNA as a cancer biomarker. However, to date there is a lack of data specific...
3.
Connor A, Denroche R, Jang G, Lemire M, Zhang A, Chan-Seng-Yue M, et al.
Cancer Cell . 2019 Jan; 35(2):267-282.e7. PMID: 30686769
We integrated clinical, genomic, and transcriptomic data from 224 primaries and 95 metastases from 289 patients to characterize progression of pancreatic ductal adenocarcinoma (PDAC). Driver gene alterations and mutational and...
4.
Abelson S, Collord G, Ng S, Weissbrod O, Mendelson Cohen N, Niemeyer E, et al.
Nature . 2018 Jul; 559(7714):400-404. PMID: 29988082
The incidence of acute myeloid leukaemia (AML) increases with age and mortality exceeds 90% when diagnosed after age 65. Most cases arise without any detectable early symptoms and patients usually...
5.
Medrano M, Communal L, Brown K, Iwanicki M, Normand J, Paterson J, et al.
Cell Rep . 2017 Mar; 18(10):2343-2358. PMID: 28273451
The degree of genetic aberrations characteristic of high-grade serous ovarian cancer (HGSC) makes identification of the molecular features that drive tumor progression difficult. Here, we perform genome-wide RNAi screens and...