Paul Jorgensen
Overview
Explore the profile of Paul Jorgensen including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
2409
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0
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Recent Articles
1.
Son S, Tzur A, Weng Y, Jorgensen P, Kim J, Kirschner M, et al.
Nat Methods
. 2012 Aug;
9(9):910-2.
PMID: 22863882
We introduce a microfluidic system for simultaneously measuring single-cell mass and cell cycle progression over multiple generations. We use this system to obtain over 1,000 h of growth data from...
2.
Yanai I, Peshkin L, Jorgensen P, Kirschner M
Dev Cell
. 2011 Apr;
20(4):483-96.
PMID: 21497761
Changes in gene expression are thought to be important for morphological evolution, though little is known about the nature or magnitude of the differences. Here, we examine Xenopus laevis and...
3.
Vastag L, Jorgensen P, Peshkin L, Wei R, Rabinowitz J, Kirschner M
PLoS One
. 2011 Feb;
6(2):e16881.
PMID: 21347444
A rapid series of synchronous cell divisions initiates embryogenesis in many animal species, including the frog Xenopus laevis. After many of these cleavage cycles, the nuclear to cytoplasmic ratio increases...
4.
Tzur A, Moore J, Jorgensen P, Shapiro H, Kirschner M
PLoS One
. 2011 Feb;
6(1):e16053.
PMID: 21283800
Cell size is a defining characteristic central to cell function and ultimately to tissue architecture. The ability to sort cell subpopulations of different sizes would facilitate investigation at genomic and...
5.
Godin M, Feijo Delgado F, Son S, Grover W, Bryan A, Tzur A, et al.
Nat Methods
. 2010 Apr;
7(5):387-90.
PMID: 20383132
We used a suspended microchannel resonator (SMR) combined with picoliter-scale microfluidic control to measure buoyant mass and determine the 'instantaneous' growth rates of individual cells. The SMR measures mass with...
6.
Urdea M, Kolberg J, Wilber J, Gerwien R, Moler E, Rowe M, et al.
J Diabetes Sci Technol
. 2010 Feb;
3(4):748-55.
PMID: 20144324
Background: Improved identification of subjects at high risk for development of type 2 diabetes would allow preventive interventions to be targeted toward individuals most likely to benefit. In previous research,...
7.
Lee T, Jorgensen P, Bognar A, Peyraud C, Thomas D, Tyers M
Mol Biol Cell
. 2009 Nov;
21(3):456-69.
PMID: 19940020
Met4 is the transcriptional activator of the sulfur metabolic network in Saccharomyces cerevisiae. Lacking DNA-binding ability, Met4 must interact with proteins called Met4 cofactors to target promoters for transcription. Two...
8.
Milo R, Jorgensen P, Moran U, Weber G, Springer M
Nucleic Acids Res
. 2009 Oct;
38(Database issue):D750-3.
PMID: 19854939
BioNumbers (http://www.bionumbers.hms.harvard.edu) is a database of key numbers in molecular and cell biology--the quantitative properties of biological systems of interest to computational, systems and molecular cell biologists. Contents of the...
9.
Jorgensen P, Steen J, Steen H, Kirschner M
Development
. 2009 Apr;
136(9):1539-48.
PMID: 19363155
Little is known about how metabolism changes during development. For most animal embryos, yolk protein is a principal source of nutrition, particularly of essential amino acids. Within eggs, yolk is...
10.