Paul J Reier
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Explore the profile of Paul J Reier including associated specialties, affiliations and a list of published articles.
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40
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1652
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Recent Articles
11.
Lee K, Lane M, Dougherty B, Mercier L, Sandhu M, Sanchez J, et al.
Exp Neurol
. 2013 Nov;
251:47-57.
PMID: 24192152
Rat fetal spinal cord (FSC) tissue, naturally enriched with interneuronal progenitors, was introduced into high cervical, hemi-resection (Hx) lesions. Electrophysiological analyses were conducted to determine if such grafts exhibit physiologically-patterned...
12.
Lee K, Dougherty B, Sandhu M, Lane M, Reier P, Fuller D
Exp Neurol
. 2013 Aug;
249:20-32.
PMID: 23954215
Cervical spinal cord injury (SCI) dramatically disrupts synaptic inputs and triggers biochemical, as well as morphological, plasticity in relation to the phrenic motor neuron (PhMN) pool. Accordingly, our primary purpose...
13.
Kwon B, Soril L, Bacon M, Beattie M, Blesch A, Bresnahan J, et al.
Exp Neurol
. 2013 Jun;
248:30-44.
PMID: 23727091
Cellular therapies represent a novel treatment approach for spinal cord injury (SCI), with many different cellular substrates showing promise in preclinical animal models of SCI. Considerable interest therefore exists to...
14.
Reier P, Lane M, Hall E, Teng Y, Howland D
Handb Clin Neurol
. 2012 Oct;
109:411-33.
PMID: 23098728
Advances in the neurobiology of spinal cord injury (SCI) have prompted increasing attention to opportunities for moving experimental strategies towards clinical applications. Preclinical studies are the centerpiece of the translational...
15.
Bose P, Hou J, Parmer R, Reier P, Thompson F
Front Physiol
. 2012 Aug;
3:258.
PMID: 22934014
Spasticity is an important problem that complicates daily living in many individuals with spinal cord injury (SCI). While previous studies in human and animals revealed significant improvements in locomotor ability...
16.
Elmallah M, Falk D, Lane M, Conlon T, Lee K, Shafi N, et al.
Hum Gene Ther Methods
. 2012 Jun;
23(2):148-56.
PMID: 22693957
Retrograde viral transport (i.e., muscle to motoneuron) enables targeted gene delivery to specific motor pools. Recombinant adeno-associated virus serotype 9 (AAV9) robustly infects motoneurons, but the retrograde transport capabilities of...
17.
Dougherty B, Lee K, Lane M, Reier P, Fuller D
J Appl Physiol (1985)
. 2011 Oct;
112(1):96-105.
PMID: 22033536
Spinal cord hemisection at C2 (C2HS) severs bulbospinal inputs to ipsilateral phrenic motoneurons causing transient hemidiaphragm paralysis. The spontaneous crossed-phrenic phenomenon (sCPP) describes the spontaneous recovery of ipsilateral phrenic bursting...
18.
Qiu K, Falk D, Reier P, Byrne B, Fuller D
Mol Ther
. 2011 Oct;
20(1):21-7.
PMID: 22008916
Pompe disease is a form of muscular dystrophy due to lysosomal storage of glycogen caused by deficiency of acid α-glucosidase (GAA). Respiratory failure in Pompe disease has been attributed to...
19.
Lane M, Lee K, Salazar K, OSteen B, Bloom D, Fuller D, et al.
Exp Neurol
. 2011 Oct;
235(1):197-210.
PMID: 21963673
The consequences of spinal cord injury (SCI) are often viewed as the result of white matter damage. However, injuries occurring at any spinal level, especially in cervical and lumbar enlargement...
20.
Lee K, Qiu K, Sandhu M, Elmallah M, Falk D, Lane M, et al.
Front Physiol
. 2011 Jul;
2:31.
PMID: 21747768
Pompe disease is a lysosomal storage disorder associated with systemic deficiency of acid α-glucosidase (GAA). Respiratory-related problems in Pompe disease include hypoventilation and upper airway dysfunction. Although these problems have...