Paul H Naccache
Overview
Explore the profile of Paul H Naccache including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
44
Citations
622
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Vitry J, Pare G, Murru A, Charest-Morin X, Maaroufi H, McLeish K, et al.
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34638548
CLEC12A is a myeloid inhibitory receptor that negatively regulates inflammation in mouse models of autoimmune and autoinflammatory arthritis. Reduced CLEC12A expression enhances myeloid cell activation and inflammation in CLEC12A knock-out...
2.
Pare G, Vitry J, Merchant M, Vaillancourt M, Murru A, Shen Y, et al.
Front Immunol
. 2021 Jul;
12:650808.
PMID: 34234773
The myeloid inhibitory C-type lectin receptor CLEC12A limits neutrophil activation, pro-inflammatory pathways and disease in mouse models of inflammatory arthritis by a molecular mechanism that remains poorly understood. We addressed...
3.
Pare G, Vitry J, Marceau F, Vaillancourt M, Winter P, Bachelard H, et al.
Biochem Pharmacol
. 2020 Jun;
180:114125.
PMID: 32598947
Background: Colchicine is routinely used for its anti-inflammatory properties to treat gout and Familial Mediterranean fever. More recently, it was also shown to be of therapeutic benefit for another group...
4.
Fernandes M, Naccache P
Front Immunol
. 2018 Sep;
9:1883.
PMID: 30177932
Inhibitory receptors are key regulators of immune responses. Aberrant inhibitory receptor function can either lead to an exacerbated or defective immune response. Several regulatory mechanisms involved in the inflammatory reaction...
5.
Rousseau L, Pare G, Lachhab A, Naccache P, Marceau F, Tessier P, et al.
J Leukoc Biol
. 2017 May;
102(3):805-813.
PMID: 28550118
Gout is one of the most painful types of arthritis that arises when the body mounts an acute inflammatory reaction against a crystallized form of uric acid known as monosodium...
6.
Van Avondt K, van der Linden M, Naccache P, Egan D, Meyaard L
J Immunol
. 2016 Mar;
196(9):3686-94.
PMID: 27016607
In response to microbial invasion, neutrophils release neutrophil extracellular traps (NETs) to trap and kill extracellular microbes. Alternatively, NET formation can result in tissue damage in inflammatory conditions and may...
7.
Naccache P, Fernandes M
Eur J Immunol
. 2015 Dec;
46(1):52-5.
PMID: 26635275
Neutrophil extracellular traps play a key role in defense against extracellular pathogens. The release of these chromatin structures, that contain a combination of cytoplasmic and granule proteins, is known as...
8.
Naccache P, Lefebvre J
Blood
. 2014 Jan;
123(2):154-6.
PMID: 24408205
In this issue of Blood, Sapey et al. report that the human polymorphonuclear neutrophil leukocyte (or neutrophil) undergoes an age-related loss of its ability to migrate up chemotactic gradients, a...
9.
Rollet-Labelle E, Vaillancourt M, Marois L, Newkirk M, Poubelle P, Naccache P
J Inflamm (Lond)
. 2013 Aug;
10(1):27.
PMID: 23902799
Background: Rheumatoid arthritis is characterized by the presence of circulating auto-antibodies, including rheumatoid factors, which recognize the Fc portion of IgGs. The neutrophil is the most abundant circulating leukocyte and...
10.
Gagne V, Marois L, Levesque J, Galarneau H, Lahoud M, Caminschi I, et al.
Arthritis Res Ther
. 2013 Jul;
15(4):R73.
PMID: 23837669
Introduction: Monosodium urate crystals (MSU), the etiological agent of gout, are one of the most potent proinflammatory stimuli for neutrophils. The modulation of MSU-induced neutrophil activation by inhibitory receptors remains...