Paul D van Helden
Overview
Explore the profile of Paul D van Helden including associated specialties, affiliations and a list of published articles.
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246
Citations
6666
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Recent Articles
1.
Mutavhatsindi H, Manyelo C, Snyders C, van Rensburg I, Kidd M, Stanley K, et al.
J Infect
. 2024 May;
89(1):106173.
PMID: 38734311
Background: There is a need for new tools for monitoring of the response to TB treatment. Such tools may allow for tailored treatment regimens, and stratify patients initiating TB treatment...
2.
Reeve B, Ndlangalavu G, Mishra H, Palmer Z, Tshivhula H, Rockman L, et al.
Lancet Glob Health
. 2024 Apr;
12(5):e793-e803.
PMID: 38583458
Background: Tuberculosis, a major cause of death in people living with HIV, remains challenging to diagnose. Diagnostic accuracy data are scarce for promising triage and confirmatory tests such as C-reactive...
3.
Roos E, Loubser J, Kerr T, Dippenaar A, Streicher E, Olea-Popelka F, et al.
One Health
. 2024 Jan;
17:100654.
PMID: 38283183
Background: forms part of the complex and has an extensive host range and zoonotic potential. Various genotyping methods (e.g., spoligotyping) have been used to describe the molecular epidemiology of Advances...
4.
Gumbo R, Goosen W, Buss P, de Klerk-Lorist L, Lyashchenko K, Warren R, et al.
Front Immunol
. 2023 Sep;
14:1216262.
PMID: 37727792
Background: () is the causative agent of animal tuberculosis (TB) which poses a threat to many of South Africa's most iconic wildlife species, including leopards (). Due to limited tests...
5.
Reeve B, Ndlangalavu G, Mishra H, Palmer Z, Tshivhula H, Rockman L, et al.
medRxiv
. 2023 Jun;
PMID: 37333303
Background: Tuberculosis (TB), a major cause of death in people living with HIV (PLHIV), remains challenging to diagnose. Diagnostic accuracy data are lacking for promising triage tests, such as C-reactive...
6.
Gumbo R, Sylvester T, Parsons S, Buss P, Warren R, van Helden P, et al.
Front Cell Infect Microbiol
. 2022 Oct;
12:989209.
PMID: 36189358
() infection has been identified in both domestic and wild animals and may threaten the conservation of vulnerable species including African lions (). There is a need to develop accurate...
7.
Gumbo R, Sylvester T, Goosen W, Buss P, de Klerk-Lorist L, van Schalkwyk O, et al.
Pathogens
. 2022 Jul;
11(7).
PMID: 35890010
() infection in wildlife, including lions (), has implications for individual and population health. Tools for the detection of infected lions are needed for diagnosis and disease surveillance. This study...
8.
Schurz H, Glanzmann B, Bowker N, van Toorn R, Solomons R, Schoeman J, et al.
Front Neurol
. 2022 Apr;
13:820168.
PMID: 35401413
Tuberculous meningitis (TBM) is the most severe form of extrapulmonary tuberculosis (TB) that arises when a caseating meningeal granuloma discharges its contents into the subarachnoid space. It accounts for ~1%...
9.
Gumbo R, Crockett E, Goosen W, Warren R, van Helden P, Miller M, et al.
J Zoo Wildl Med
. 2022 Jan;
52(4):1113-1122.
PMID: 34998280
The lack of species-specific assays for the diagnosis of infectious diseases, such as bovine tuberculosis, poses a threat to the management of wildlife populations, especially for vulnerable species such as...
10.
Swart Y, Uren C, van Helden P, Hoal E, Moller M
Front Genet
. 2021 Nov;
12:716558.
PMID: 34721521
Pulmonary tuberculosis (TB), caused by , is a complex disease. The risk of developing active TB is in part determined by host genetic factors. Most genetic studies investigating TB susceptibility...