Paul D Lewis
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Explore the profile of Paul D Lewis including associated specialties, affiliations and a list of published articles.
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28
Citations
1463
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Recent Articles
1.
Huws A, Davies G, Lewis P, Morgan C
Clin Breast Cancer
. 2024 Dec;
PMID: 39734136
Background: Adjuvant therapy decisions in hormone receptor positive, HER2 negative breast cancer are evolving. Gene panel testing has reduced the number of patients recommended for chemotherapy by up to two...
2.
Jordan K, Mackintosh K, Davies G, Griffiths C, Lewis P, McNarry M
BMC Public Health
. 2023 Dec;
23(1):2416.
PMID: 38053057
A cornerstone of asthma management is maintaining physical activity (PA), but this may lead to increased exposure to, and deeper inhalation of, pollutants. Furthermore, children and adolescents may be more...
3.
Menzies G, Prior I, Brancale A, Reed S, Lewis P
BMC Chem
. 2021 Sep;
15(1):51.
PMID: 34521464
Background: Local sequence context is known to have an impact on the mutational pattern seen in cancer. The RAS genes and a smoking carcinogen, Benzo[a]pyrene diol epoxide (BPDE), have been...
4.
Mur L, Huws S, Cameron S, Lewis P, Lewis K
Ecancermedicalscience
. 2018 Sep;
12:866.
PMID: 30263057
The lung microbiome has been shown to reflect a range of pulmonary diseases-for example: asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Studies have now begun to show microbiological...
5.
Powell L, Pritchard M, Ferguson E, Powell K, Patel S, Rye P, et al.
NPJ Biofilms Microbiomes
. 2018 Jul;
4:13.
PMID: 29977590
Acquisition of a mucoid phenotype by sp. in the lungs of cystic fibrosis (CF) patients, with subsequent over-production of extracellular polymeric substance (EPS), plays an important role in mediating the...
6.
Cameron S, Lewis K, Huws S, Hegarty M, Lewis P, Pachebat J, et al.
PLoS One
. 2017 May;
12(5):e0177062.
PMID: 28542458
Lung cancer (LC) is the most prevalent cancer worldwide, and responsible for over 1.3 million deaths each year. Currently, LC has a low five year survival rates relative to other...
7.
Jenkins C, Lewis P, Dunstan P, Harris D
World J Gastrointest Oncol
. 2016 May;
8(5):427-38.
PMID: 27190582
Colorectal cancer (CRC) is the fourth most common cancer in the United Kingdom and is the second largest cause of cancer related death in the United Kingdom after lung cancer....
8.
Cameron S, Lewis K, Beckmann M, Allison G, Ghosal R, Lewis P, et al.
Lung Cancer
. 2016 Mar;
94:88-95.
PMID: 26973212
Objectives: Developing screening and diagnosis methodologies based on novel biomarkers should allow for the detection of the lung cancer (LC) and possibly at an earlier stage and thereby increase the...
9.
Cameron S, Lewis K, Huws S, Lin W, Hegarty M, Lewis P, et al.
PLoS One
. 2016 Feb;
11(2):e0149095.
PMID: 26872143
Chronic Obstructive Pulmonary Disease (COPD) is a major source of mortality and morbidity worldwide. The microbiome associated with this disease may be an important component of the disease, though studies...
10.
Pritchard M, Powell L, Menzies G, Lewis P, Hawkins K, Wright C, et al.
Mol Pharm
. 2016 Feb;
13(3):863-72.
PMID: 26833139
The host- and bacteria-derived extracellular polysaccharide coating of the lung is a considerable challenge in chronic respiratory disease and is a powerful barrier to effective drug delivery. A low molecular...