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Paul D Hoeprich

Explore the profile of Paul D Hoeprich including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 367
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Recent Articles
11.
Baker S, Hopkins R, Blanchette C, Walsworth V, Sumbad R, Fischer N, et al.
J Am Chem Soc . 2009 May; 131(22):7508-9. PMID: 19449869
Hydrogenases constitute a promising class of enzymes for ex vivo hydrogen production. Implementation of such applications is currently hindered by oxygen sensitivity and, in the case of membrane-bound hydrogenases (MBHs),...
12.
Fischer N, Blanchette C, Chromy B, Kuhn E, Segelke B, Corzett M, et al.
Bioconjug Chem . 2009 Feb; 20(3):460-5. PMID: 19239247
Nanolipoprotein particles (NLPs) are nanometer-sized, discoidal particles that self-assemble from purified apolipoprotein and phospholipid. Their size and facile functionalization suggest potential application of NLPs as platforms for the presentation and...
13.
Blanchette C, Cappuccio J, Kuhn E, Segelke B, Benner W, Chromy B, et al.
Biochim Biophys Acta . 2008 Dec; 1788(3):724-31. PMID: 19109924
To better understand the incorporation of membrane proteins into discoidal nanolipoprotein particles (NLPs) we have used atomic force microscopy (AFM) to image and analyze NLPs assembled in the presence of...
14.
Cappuccio J, Blanchette C, Sulchek T, Arroyo E, Kralj J, Hinz A, et al.
Mol Cell Proteomics . 2008 Jul; 7(11):2246-53. PMID: 18603642
Here we demonstrate rapid production of solubilized and functional membrane protein by simultaneous cell-free expression of an apolipoprotein and a membrane protein in the presence of lipids, leading to the...
15.
Katzen F, Fletcher J, Yang J, Kang D, Peterson T, Cappuccio J, et al.
J Proteome Res . 2008 Jun; 7(8):3535-42. PMID: 18557639
We report a cell-free approach for expressing and inserting integral membrane proteins into water-soluble particles composed of discoidal apolipoprotein-lipid bilayers. Proteins are inserted into the particles, circumventing the need of...
16.
Blanchette C, Law R, Benner W, Pesavento J, Cappuccio J, Walsworth V, et al.
J Lipid Res . 2008 Apr; 49(7):1420-30. PMID: 18403317
Self-assembly of purified apolipoproteins and phospholipids results in the formation of nanometer-sized lipoprotein complexes, referred to as nanolipoprotein particles (NLPs). These bilayer constructs are fully soluble in aqueous environments and...
17.
Chromy B, Arroyo E, Blanchette C, Bench G, Benner H, Cappuccio J, et al.
J Am Chem Soc . 2007 Oct; 129(46):14348-54. PMID: 17963384
Spontaneous interaction of purified apolipoproteins and phospholipids results in formation of lipoprotein particles with nanometer-sized dimensions; we refer to these assemblies as nanolipoprotein particles or NLPs. These bilayer constructs can...