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Paul Cottu

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Articles 126
Citations 2442
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Recent Articles
1.
Helal C, Djerroudi L, Ramtohul T, Laas E, Vincent-Salomon A, Jin M, et al.
NPJ Breast Cancer . 2025 Feb; 11(1):15. PMID: 39948122
Pathological complete response (pCR) after neoadjuvant chemoimmunotherapy (NACi) is associated with improved patient outcomes in early triple-negative breast cancer (TNBC). This study aimed to identify factors associated with pCR after...
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Cottu P, Cheeseman S, Hall P, Wockel A, Scholz C, Bria E, et al.
Breast Cancer Res Treat . 2024 Oct; 209(2):419-430. PMID: 39427280
Purpose: To characterize real-world attrition rates across first-line (1L) to third-line (3L) therapies in patients with HER2-positive (HER2 +) metastatic breast cancer (mBC) receiving routine care in seven hospital systems...
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Piffoux M, Jacquemin J, Petera M, Durand S, Abila A, Centeno D, et al.
Clin Cancer Res . 2024 Aug; 30(20):4654-4666. PMID: 39106085
Purpose: Long-term treatment-related toxicities, such as neurologic and metabolic toxicities, are major issues in breast cancer. We investigated the interest of metabolomic profiling to predict toxicities. Experimental Design: Untargeted high-resolution...
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Bouziane J, Loap P, Cottu P, Escalup L, Kirova Y
Am J Clin Oncol . 2024 Jul; 47(12):574-579. PMID: 38961527
Objectives: In the recent MONALEESA-2, MONALEESA-3, and MONALEESA-7 clinical trials, the addition of ribociclib, a CDK4/6 inhibitor, to standard endocrine therapy significantly improved progression-free survival (PFS) compared with hormone therapy...
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Camilleri G, Delrieu L, Bouleuc C, Pierga J, Cottu P, Berger F, et al.
Clin Nutr . 2024 Jun; 43(8):1710-1718. PMID: 38908032
Background: Malnutrition and sarcopenia are challenges for patients with metastatic breast cancer and have been proposed as independent prognostic factors. Very few studies have addressed the temporal evolution of these...
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Sandoval J, Franzoi M, Di Meglio A, Ferreira A, Viansone A, Andre F, et al.
J Clin Oncol . 2024 Jun; 42(24):2908-2917. PMID: 38889372
Purpose: Socioeconomic status (SES) influences the survival outcomes of patients with early breast cancer (EBC). However, limited research investigates social inequalities in their quality of life (QoL). This study examines...
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Soldato D, Michiels S, Havas J, Di Meglio A, Pagliuca M, Franzoi M, et al.
J Clin Oncol . 2024 Jun; 42(25):3022-3032. PMID: 38838281
Purpose: Postdiagnosis exercise is associated with lower breast cancer (BC) mortality but its link with risk of recurrence is less clear. We investigated the impact and dose-response relationship of exercise...
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Giacchetti S, Laas E, Bachelot T, Lemonnier J, Andre F, Cameron D, et al.
EBioMedicine . 2024 May; 104:105141. PMID: 38718683
Background: Circadian rhythms regulate cellular physiology and could influence the efficacy of endocrine therapy (ET) in breast cancer (BC). We prospectively tested this hypothesis within the UNIRAD adjuvant phase III...
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De Moura A, Loirat D, Vaillant S, Korbi S, Kiavue N, Bello Roufai D, et al.
Breast Cancer . 2024 Apr; 31(4):572-580. PMID: 38600429
Background: Sacituzumab govitecan (SG) has been approved by FDA in April 2021 for pre-treated metastatic triple-negative breast cancer (mTNBC), following the ASCENT trial results. Methods: We set up an ambispective...