Paul Chi-Lui Ho
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Explore the profile of Paul Chi-Lui Ho including associated specialties, affiliations and a list of published articles.
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728
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Recent Articles
1.
Thuya W, Cao Y, Ho P, Wong A, Wang L, Zhou J, et al.
Cytokine Growth Factor Rev
. 2025 Feb;
PMID: 39893129
The IL-6/JAK/STAT3 signaling pathway is a key regulator of tumor progression, immune evasion, and therapy resistance in various cancers. Frequently dysregulated in malignancies, this pathway drives cancer cell growth, survival,...
2.
Kong S, Lim S, Ching J, Ho P
J Pharm Biomed Anal
. 2024 Nov;
253:116561.
PMID: 39514984
This study compared the effectiveness of capillary dried blood spots (DBS) versus venous DBS in detecting metabolic changes related to drug-resistant epilepsy (DRE). DBS samples were collected from 142 epilepsy...
3.
Cheng L, Zhang L, Wang X, Wang Y, Yu J, Li M, et al.
Pharmacol Res
. 2024 Sep;
209:107419.
PMID: 39284428
Hepatocellular carcinoma (HCC) stands as the sixth most prevalent cancer and the third leading cause of cancer mortality globally. Despite surgical resection being the preferred approach for early-stage HCC, most...
4.
Wang X, Zhang L, Cheng L, Wang Y, Li M, Yu J, et al.
Cancer Lett
. 2024 Aug;
601:217184.
PMID: 39142499
Prostate cancer (PCa) is the second most prevalent cancer in men worldwide, presenting a significant global public health challenge that necessitates early detection and personalized treatment. Recently, non-invasive liquid biopsy...
5.
Ng M, Song Z, Venkatesan G, Rodriguez-Cuenca S, West J, Yang S, et al.
Sci Rep
. 2024 Feb;
14(1):4932.
PMID: 38418847
One potential approach for treating obesity is to increase energy expenditure in brown and white adipose tissue. Here we aimed to achieve this outcome by targeting mitochondrial uncoupler compounds selectively...
6.
Yang S, Lin H, Zhang L, Ho P
Int J Pharm
. 2024 Feb;
654:123945.
PMID: 38403088
This study aimed to develop an innovative dosage form for 10-hydroxycamptothecin (HCPT), a chemotherapeutic agent with limited aqueous solubility and stability, to enhance its parenteral delivery and targeting to hepatic...
7.
Zailani N, Ho P
Eur J Drug Metab Pharmacokinet
. 2023 Jul;
48(5):467-494.
PMID: 37495930
This review provides an overview on the current applications of dried blood spots (DBS) as matrices for therapeutic drug (TDM) and drug or disease response monitoring (DRM). Compared with conventional...
8.
Zhang L, Wong L, Wong P, Shen W, Yang S, Huang L, et al.
Brain Behav Immun Health
. 2023 Feb;
28:100599.
PMID: 36817510
Baicalein (BE) has both antioxidant and anti-inflammatory effects. It has also been reported able to improve cerebral blood circulation in brain ischemic injury. However, its chronic efficacy and metabolomics in...
9.
Thuya W, Kong L, Syn N, Ding L, Cheow E, Wong R, et al.
Theranostics
. 2023 Jan;
13(2):621-638.
PMID: 36632230
: Metastasis is a complex process with a molecular underpinning that remains unclear. We hypothesize that cargo proteins conducted by extracellular vesicles (EVs) released from tumors may confer growth and...
10.
Wong H, Lee C, Ho P
J Pharm Pharmacol
. 2022 Jul;
74(9):1220-1229.
PMID: 35789390
Objectives: Several common wound healing models have been used to evaluate wound healing agents and formulations, namely: conditioned media (CM), transwell co-cultures (TWCC) and co-cultures (CC) in a monolayer. However,...