Paul C Porter
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Explore the profile of Paul C Porter including associated specialties, affiliations and a list of published articles.
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12
Citations
323
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Recent Articles
1.
Landers C, Tung H, Knight J, Madison M, Wu Y, Zeng Z, et al.
J Biol Chem
. 2019 Apr;
294(22):8834-8847.
PMID: 30992366
Proteinases are essential drivers of allergic airway disease and innate antifungal immunity in part through their ability cleave the clotting factor fibrinogen (FBG) into fibrinogen cleavage products (FCPs) that signal...
2.
Huq R, Samuel E, Sikkema W, Nilewski L, Lee T, Tanner M, et al.
Sci Rep
. 2016 Sep;
6:33808.
PMID: 27654170
Autoimmune diseases mediated by a type of white blood cell-T lymphocytes-are currently treated using mainly broad-spectrum immunosuppressants that can lead to adverse side effects. Antioxidants represent an alternative approach for...
3.
Porter P, Lim D, Maskatia Z, Mak G, Tsai C, Citardi M, et al.
J Allergy Clin Immunol
. 2014 Jun;
134(2):325-31.
PMID: 24928648
Background: Environmental fungi have been linked to TH2 cell-related airway inflammation and the TH2-associated chronic airway diseases asthma, chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP), and allergic fungal rhinosinusitis (AFRS),...
4.
Koshy S, Huq R, Tanner M, Atik M, Porter P, Khan F, et al.
J Biol Chem
. 2014 Mar;
289(18):12623-32.
PMID: 24644290
Allergic asthma is a chronic inflammatory disease of the airways. Of the different lower airway-infiltrating immune cells that participate in asthma, T lymphocytes that produce Th2 cytokines play important roles...
5.
Shaw J, Fakhri S, Citardi M, Porter P, Corry D, Kheradmand F, et al.
Am J Respir Crit Care Med
. 2013 Jun;
188(4):432-9.
PMID: 23805875
Rationale: Chronic rhinosinusitis (CRS) without nasal polyps (CRSsNP) and CRS with nasal polyps (CRSwNP) are associated with Th1 and Th2 cytokine polarization, respectively; however, the pathophysiology of CRS remains unclear....
6.
Mak G, Porter P, Bandi V, Kheradmand F, Corry D
Clin Immunol
. 2013 Jan;
146(2):77-83.
PMID: 23280490
The etiology of status asthmaticus (SA), a complication of severe asthma, is unknown. Fungal exposure, as measured by fungal atopy, is a major risk factor for developing asthma, but the...
7.
Porter P, Roberts L, Fields A, Knight M, Qian Y, Delclos G, et al.
Infect Immun
. 2011 Aug;
79(11):4459-71.
PMID: 21875960
Mucosal immune responses to fungal infection range from T helper type 2 (Th2) cell-directed allergic inflammation to Th1-predominant neutrophilic inflammation, but the mechanisms directing these divergent mucosal immune outcomes and...
8.
Porter P, Yang T, Luong A, Delclos G, Abramson S, Kheradmand F, et al.
Biochim Biophys Acta
. 2011 Jun;
1810(11):1059-65.
PMID: 21712069
Background: Asthma and related respiratory tract allergic diseases are among the most common chronic diseases of adults and children. Despite their importance, disease course cannot be predicted and treatment remains...
9.
Porter P, Ongeri V, Luong A, Kheradmand F, Corry D
Trends Immunol
. 2011 Jan;
32(2):43-9.
PMID: 21239229
Asthma and chronic sinusitis are inexplicably common airway diseases that are linked to atopy and allergic inflammation. T helper type 2 (Th2) cells and the associated cytokines are believed to...
10.
Porter P, Clark D, McDaniel L, McGregor W, States J
DNA Repair (Amst)
. 2005 Sep;
5(1):61-70.
PMID: 16140041
Immortalized cells frequently have disruptions of p53 activity and lack p53-dependent nucleotide excision repair (NER). We hypothesized that telomerase immortalization would not alter p53-mediated ultraviolet light (UV)-induced DNA damage responses....