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Paul A Tambyah

Explore the profile of Paul A Tambyah including associated specialties, affiliations and a list of published articles. Areas
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Articles 142
Citations 3183
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Recent Articles
11.
Fong S, Yeo N, Chan Y, Goh Y, Amrun S, Ang N, et al.
J Clin Immunol . 2021 Nov; 42(2):230-231. PMID: 34837161
No abstract available.
12.
Chia D, Lim Z, Ang J, Tambyah P, Lau K, Ong J, et al.
Br J Surg . 2021 Nov; 109(1):15-20. PMID: 34792098
No abstract available.
13.
Fong S, Yeo N, Chan Y, Goh Y, Amrun S, Ang N, et al.
J Clin Immunol . 2021 Oct; 42(2):214-229. PMID: 34716845
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) that have become dominant as the pandemic progresses bear the ORF8 mutation together with multiple spike mutations. A...
14.
Zhao H, Zhang Y, Chen Y, Ho N, Sundah N, Natalia A, et al.
Biosens Bioelectron . 2021 Sep; 194:113629. PMID: 34534949
Accurate and accessible nucleic acid diagnostics is critical to reducing the spread of COVID-19 and resuming socioeconomic activities. Here, we present an integrated platform for the direct detection of SARS-CoV-2...
15.
Ang A, Luhung I, Ahidjo B, Drautz-Moses D, Tambyah P, Mok C, et al.
Indoor Air . 2021 Sep; 32(1):e12930. PMID: 34519380
Reliable methods to detect the presence of SARS-CoV-2 at venues where people gather are essential for epidemiological surveillance to guide public policy. Communal screening of air in a highly crowded...
16.
Chen Y, Sundah N, Ho N, Natalia A, Liu Y, Miow Q, et al.
Adv Sci (Weinh) . 2021 Jul; 8(18):e2101155. PMID: 34278742
Accessible and adaptable nucleic acid diagnostics remains a critical challenge in managing the evolving COVID-19 pandemic. Here, an integrated molecular nanotechnology that enables direct and programmable detection of SARS-CoV-2 RNA...
17.
Chan Y, Young B, Fong S, Ding Y, Goh Y, Chee R, et al.
Front Immunol . 2021 Jul; 12:680188. PMID: 34262564
A significant proportion of COVID-19 patients will progress to critical illness requiring invasive mechanical ventilation. This accentuates the need for a therapy that can reduce the severity of COVID-19. Clinical...
18.
Miow Q, Vallejo A, Wang Y, Hong J, Bai C, Teo F, et al.
J Clin Invest . 2021 Jun; 131(15). PMID: 34128838
BACKGROUNDMatrix metalloproteinases (MMPs) are key regulators of tissue destruction in tuberculosis (TB) and may be targets for host-directed therapy. We conducted a phase II double-blind, randomized, controlled trial investigating doxycycline,...
19.
Cai Y, Venkatachalam I, Kwa A, Tambyah P, Hsu L, Marimuthu K, et al.
Infect Control Hosp Epidemiol . 2021 May; 43(9):1245-1248. PMID: 34016198
We estimated the annual bed days lost and economic burden of healthcare-associated infections to Singapore hospitals using Monte Carlo simulation. The mean (standard deviation) cost of a single healthcare-associated infection...
20.
Young B, Wei W, Fong S, Mak T, Anderson D, Chan Y, et al.
EBioMedicine . 2021 Apr; 66:103319. PMID: 33840632
Background: Host determinants of severe coronavirus disease 2019 include advanced age, comorbidities and male sex. Virologic factors may also be important in determining clinical outcome and transmission rates, but limited...