Paul A Mueller
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Explore the profile of Paul A Mueller including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
183
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Recent Articles
1.
Mueller P, Bergstrom P, Rosario S, Heard M, Pamir N
J Nutr
. 2024 Jan;
154(4):1130-1140.
PMID: 38237669
Background: Fish oil with the ω-3 fatty acids EPA and DHA is an FDA-approved treatment of patients with severe hypertriglyceridemia. Furthermore, EPA is an FDA-approved treatment of patients with high...
2.
Zheng T, Kohs T, Mueller P, Pang J, Reitsma S, Parra-Izquierdo I, et al.
Blood Adv
. 2022 Oct;
7(8):1366-1378.
PMID: 36219587
Low-density lipoprotein (LDL) contributes to atherogenesis and cardiovascular disease through interactions with peripheral blood cells, especially platelets. However, mechanisms by which LDL affects platelet activation and atherothrombosis, and how to...
3.
Mueller P, Yerkes E, Bergstrom P, Rosario S, Hay J, Pamir N
Sci Rep
. 2022 Jun;
12(1):9138.
PMID: 35650291
High levels of circulating Lipoprotein (a) [Lp(a)] are an independent risk factor for CVD. One of the major limitations to investigating Lp(a) biology is the need for large volumes of...
4.
Mueller P, Kojima Y, Huynh K, Maldonado R, Ye J, Tavori H, et al.
Arterioscler Thromb Vasc Biol
. 2021 Nov;
42(1):e1-e9.
PMID: 34758632
Objective: Antibody blockade of the "do not eat me" signal CD47 (cluster of differentiation 47) enhances efferocytosis and reduces lesion size and necrotic core formation in murine atherosclerosis. TNF (Tumor...
5.
Oleaga C, Shapiro M, Hay J, Mueller P, Miles J, Huang C, et al.
J Am Coll Cardiol
. 2021 Oct;
78(14):1437-1449.
PMID: 34593126
Background: Monoclonal antibodies against proprotein convertase subtilisin/kexin type 9 (PCSK9i) lower LDL-C by up to 60% and increase plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) levels by 10-fold. Objectives: The...
6.
Velho T, Lovell P, Friedrich S, Olson C, Miles J, Mueller P, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(18).
PMID: 33903244
The low-density lipoprotein receptor (LDLR) is key to cellular cholesterol uptake and is also the main receptor for the vesicular stomatitis virus glycoprotein (VSV G). Here we show that in...
7.
Oleaga C, Hay J, Gurcan E, David L, Mueller P, Tavori H, et al.
J Lipid Res
. 2021 Jan;
62:100003.
PMID: 33429337
Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates cholesterol metabolism by inducing the degradation of hepatic low density lipoprotein receptors (LDLRs). Plasma PCSK9 has 2 main molecular forms: a 62 kDa...
8.
Ngo A, Jordan K, Mueller P, Hagen M, Reitsma S, Puy C, et al.
J Thromb Haemost
. 2021 Jan;
19(4):1001-1017.
PMID: 33421301
Background: Human coagulation factor (F) XI deficiency, a defect of the contact activation system, protects against venous thrombosis, stroke, and heart attack, whereas FXII, plasma prekallikrein, or kininogen deficiencies are...
9.
Ozawa K, Muller M, Varlamov O, Tavori H, Packwood W, Mueller P, et al.
JACC Basic Transl Sci
. 2020 Nov;
5(10):1017-1028.
PMID: 33145464
This study used in vivo molecular imaging to characterize endotheliall activation attributable to von Willebrand factor (vWF)-mediated platelet adhesion in atherosclerosis. In atherosclerotic mice lacking the low-density lipoprotein receptor on...
10.
Mueller P, Yang L, Ubele M, Mao G, Brandon J, Vandra J, et al.
Arterioscler Thromb Vasc Biol
. 2019 Sep;
39(11):2261-2272.
PMID: 31533471
Objective: Genome-wide association studies identified novel loci in (phospholipid phosphatase 3) that associate with coronary artery disease risk independently of traditional risk factors. encodes LPP3 (lipid phosphate phosphatase 3), a...