Paul A Hessian
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Explore the profile of Paul A Hessian including associated specialties, affiliations and a list of published articles.
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21
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272
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Recent Articles
1.
Stamp L, Keating P, Frampton C, Barclay M, Fanning N, Millier M, et al.
J Rheumatol
. 2024 Jan;
51(3):242-249.
PMID: 38224989
Objectives: To determine the influence of patient characteristics and disease activity on adalimumab (ADA) concentrations; to assess the relationships between ADA concentrations, the presence of antidrug antibodies (ADAb), and disease...
2.
Wiles A, Mehta S, Millier M, Woolley A, Li K, Parker K, et al.
Arthritis Res Ther
. 2023 Apr;
25(1):62.
PMID: 37060003
Background: The p53 isoform Δ133p53β is known to be associated with cancers driven by inflammation. Many of the features associated with the development of inflammation in rheumatoid arthritis (RA) parallel...
3.
Millier M, Fanning N, Frampton C, Stamp L, Hessian P
Arthritis Res Ther
. 2022 Feb;
24(1):57.
PMID: 35219333
Objectives: TNF-α inhibitors are widely used in rheumatoid arthritis (RA) with varying success. Response to TNF-α inhibition may reflect the evolution of rheumatoid inflammation through fluctuating stages of TNF-α dependence....
4.
Millier M, Lazaro K, Stamp L, Hessian P
Genes Immun
. 2020 Jun;
21(4):249-259.
PMID: 32518420
We aimed to assess expression of genes encoding the heterodimeric IL-27 cytokine and constituent subunits of the Il-27 receptor in rheumatoid arthritis (RA), including in extra-articular, subcutaneous rheumatoid nodules. Comparing...
5.
McKelvey K, Millier M, Doyle T, Stamp L, Highton J, Hessian P
PLoS One
. 2018 Aug;
13(8):e0202135.
PMID: 30114200
Objective: To determine whether the expression of IL17A and CD21L genes in inflamed rheumatoid synovia is associated with the neogenesis of ectopic lymphoid follicle-like structures (ELS), and if this aids...
6.
Eason C, Adams S, Puddick J, Romanazzi D, Miller M, King N, et al.
Vet Sci
. 2018 Mar;
5(2).
PMID: 29584640
The therapeutic benefits of Greenshell™ mussel (GSM; ) preparations have been studied using test systems, animal models, and human clinical trials focusing mainly on anti-inflammatory and anti-arthritic effects. Activity is...
7.
Millier M, Stamp L, Hessian P
Sci Rep
. 2017 Dec;
7(1):17235.
PMID: 29222437
Subtle molecular differences indicate the heterogeneity present in a number of disease settings. Digital-PCR (dPCR) platforms achieve the necessary levels of sensitivity and accuracy over standard quantitative RT-PCR (qPCR) that...
8.
Houlder E, Millier M, Highton J, Gwynne-Jones D, Stamp L, Hessian P
Clin Exp Rheumatol
. 2017 Jun;
35(6):943-947.
PMID: 28598776
Objectives: We sought further understanding of the association between methotrexate (MTX) therapy and accelerated development of subcutaneous rheumatoid nodules. The objective was to establish expression of genes involved in the...
9.
Stamp L, Hazlett J, Highton J, Hessian P
J Rheumatol
. 2013 Jul;
40(9):1519-22.
PMID: 23858048
Objective: To determine whether methotrexate (MTX) affects the expression of genes involved in the transport [SLC19A1 (RFC1), ABCB1 (MDR1), ABCC1 (multidrug resistance proteins 1), ABCG2 (BCRP)], metabolism [γ-glutamyl hydrolase (GGH),...
10.
Kazantseva M, Highton J, Stamp L, Hessian P
Arthritis Res Ther
. 2012 Oct;
14(5):R208.
PMID: 23036591
Introduction: Smoking increases the risk of developing rheumatoid arthritis (RA) and affects the severity of established RA. Smoking can impact on Th17 lymphocyte differentiation and function through activation of the...