Patryk Janus
Overview
Explore the profile of Patryk Janus including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
156
Followers
0
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Recent Articles
1.
Janus P, Kus P, Jaksik R, Vydra N, Toma-Jonik A, Gramatyka M, et al.
Cell Commun Signal
. 2024 Oct;
22(1):522.
PMID: 39468555
Background: Transforming growth factor beta (TGFβ) is important for the morphogenesis and secretory function of the mammary gland. It is one of the main activators of the epithelial-mesenchymal transition (EMT),...
2.
An Increase in HSF1 Expression Directs Human Mammary Epithelial Cells toward a Mesenchymal Phenotype
Vydra N, Toma-Jonik A, Janus P, Mrowiec K, Stokowy T, Glowala-Kosinska M, et al.
Cancers (Basel)
. 2023 Oct;
15(20).
PMID: 37894333
HSF1 is a well-known heat shock protein expression regulator in response to stress. It also regulates processes important for growth, development or tumorigenesis. We studied the HSF1 influence on the...
3.
Janus P, Kus P, Vydra N, Toma-Jonik A, Stokowy T, Mrowiec K, et al.
Cells
. 2022 Aug;
11(16).
PMID: 36010586
Heat Shock Factor 1 (HSF1), a transcription factor frequently overexpressed in cancer, is activated by proteotoxic agents and participates in the regulation of cellular stress response. To investigate how HSF1...
4.
Vydra N, Janus P, Kus P, Stokowy T, Mrowiec K, Toma-Jonik A, et al.
Elife
. 2021 Nov;
10.
PMID: 34783649
Heat shock factor 1 (HSF1), a key regulator of transcriptional responses to proteotoxic stress, was linked to estrogen (E2) signaling through estrogen receptor α (ERα). We found that an HSF1...
5.
Mrowiec K, Chadalski M, Paszek A, Vydra N, Janus P, Pietrowska M, et al.
Biochim Biophys Acta Mol Cell Res
. 2021 Jun;
1868(10):119086.
PMID: 34175335
The mouse 3110001I22Rik gene located in the first intron of Bfar is considered as a Bfar variant coding for the BFARv3 protein. However, it differs from other BFAR isoforms and...
6.
Janus P, Toma-Jonik A, Vydra N, Mrowiec K, Korfanty J, Chadalski M, et al.
Cell Death Differ
. 2020 Jan;
27(7):2280-2292.
PMID: 31996779
Heat shock can induce either cytoprotective mechanisms or cell death. We found that in certain human and mouse cells, including spermatocytes, activated heat shock factor 1 (HSF1) binds to sequences...
7.
Janus P, Mrowiec K, Vydra N, Widlak P, Toma-Jonik A, Korfanty J, et al.
Int J Mol Sci
. 2020 Jan;
21(1).
PMID: 31906015
Spermatocytes are among the most heat-sensitive cells and the exposure of testes to heat shock results in their Heat Shock Factor 1 (HSF1)-mediated apoptosis. Several lines of evidence suggest that...
8.
Vydra N, Janus P, Toma-Jonik A, Stokowy T, Mrowiec K, Korfanty J, et al.
Cancers (Basel)
. 2019 Oct;
11(10).
PMID: 31614463
Heat Shock Factor 1 (HSF1) is a key regulator of gene expression during acute environmental stress that enables the cell survival, which is also involved in different cancer-related processes. A...
9.
Toma-Jonik A, Vydra N, Janus P, Widlak W
Cell Oncol (Dordr)
. 2019 Jun;
42(5):579-589.
PMID: 31183804
Background: The p53 and HSF1 transcription factors are key players in cellular responses to stress. They activate important signaling pathways triggering adaptive mechanisms that maintain cellular homeostasis. HSF1 is mainly...
10.
Szoltysek K, Janus P, Zajac G, Stokowy T, Walaszczyk A, Widlak W, et al.
BMC Genomics
. 2018 Nov;
19(1):813.
PMID: 30419821
Background: The cellular response to ionizing radiation involves activation of p53-dependent pathways and activation of the atypical NF-κB pathway. The crosstalk between these two transcriptional networks include (co)regulation of common...