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Patryk Janus

Explore the profile of Patryk Janus including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 156
Followers 0
Related Specialties
Cell Biology
Biochemistry
Molecular Biology
Top 10 Co-Authors
Wieslawa Widlak
Natalia Vydra
Agnieszka Toma-Jonik
Piotr Widlak
Marek Kimmel
Tomasz Stokowy
Katarzyna Mrowiec
Katarzyna Szoltysek
Bartosz Wojtas
Bartlomiej Gielniewski
Published In
Genes Cells
Cancers (Basel)
BMC Syst Biol
Cell Signal
Cell Oncol (Dordr)
Affiliations
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Recent Articles
11.
The Alzheimer's disease-associated TREM2 gene is regulated by p53 tumor suppressor protein
Zajkowicz A, Gdowicz-Klosok A, Krzesniak M, Janus P, Lasut B, Rusin M
Neurosci Lett . 2018 May; 681:62-67. PMID: 29842899
TREM2 mutations evoke neurodegenerative disorders, and recently genetic variants of this gene were correlated to increased risk of Alzheimer's disease. The signaling cascade originating from the TREM2 membrane receptor includes...
12.
Pro-inflammatory cytokine and high doses of ionizing radiation have similar effects on the expression of NF-kappaB-dependent genes
Janus P, Szoltysek K, Zajac G, Stokowy T, Walaszczyk A, Widlak W, et al.
Cell Signal . 2018 Feb; 46:23-31. PMID: 29476964
The NF-κB transcription factors are activated via diverse molecular mechanisms in response to various types of stimuli. A plethora of functions associated with specific sets of target genes could be...
13.
Irradiation with UV-C inhibits TNF-α-dependent activation of the NF-κB pathway in a mechanism potentially mediated by reactive oxygen species
Szoltysek K, Walaszczyk A, Janus P, Kimmel M, Widlak P
Genes Cells . 2016 Dec; 22(1):45-58. PMID: 27976481
Pathways depending on the NF-κB transcription factor are essential components of cellular response to stress. Plethora of stimuli modulating NF-κB includes inflammatory signals, ultraviolet radiation (UV) and reactive oxygen species...
14.
Erratum to: A novel mathematical model of ATM/p53/NF-κB pathways points to the importance of the DDR switch-off mechanisms
Jonak K, Kurpas M, Szoltysek K, Janus P, Abramowicz A, Puszynski K
BMC Syst Biol . 2016 Oct; 10(1):99. PMID: 27769272
No abstract available.
15.
A novel mathematical model of ATM/p53/NF- κB pathways points to the importance of the DDR switch-off mechanisms
Jonak K, Kurpas M, Szoltysek K, Janus P, Abramowicz A, Puszynski K
BMC Syst Biol . 2016 Aug; 10(1):75. PMID: 27526774
Background: Ataxia telangiectasia mutated (ATM) is a detector of double-strand breaks (DSBs) and a crucial component of the DNA damage response (DDR) along with p53 and NF- κB transcription factors...
16.
Cross talk between cytokine and hyperthermia-induced pathways: identification of different subsets of NF-κB-dependent genes regulated by TNFα and heat shock
Janus P, Stokowy T, Jaksik R, Szoltysek K, Handschuh L, Podkowinski J, et al.
Mol Genet Genomics . 2015 May; 290(5):1979-90. PMID: 25944781
Heat shock inhibits NF-κB signaling, yet the knowledge about its influence on the regulation of NF-κB-dependent genes is limited. Using genomic approaches, i.e., expression microarrays and ChIP-Seq, we aimed to...
17.
NF-κB signaling pathway is inhibited by heat shock independently of active transcription factor HSF1 and increased levels of inducible heat shock proteins
Janus P, Pakula-Cis M, Kalinowska-Herok M, Kashchak N, Szoltysek K, Piglowski W, et al.
Genes Cells . 2011 Nov; 16(12):1168-75. PMID: 22077664
NF-κB transcription factor regulates numerous genes important for inflammation, immune responses and cell survival. HSF1 is the primary transcription factor activated under stress conditions that is responsible for induction of...