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Patrizia Hrelia

Explore the profile of Patrizia Hrelia including associated specialties, affiliations and a list of published articles. Areas
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Articles 166
Citations 2271
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Recent Articles
1.
Graziosi A, Corrieri C, Sita G, Ghelli L, Angelini S, dEmmanuele di Villa Bianca R, et al.
Sci Rep . 2025 Jan; 15(1):2722. PMID: 39837947
Environmental endocrine disruptor chemicals (EDCs) have raised significant concerns due to their potential adverse effects on human health, particularly on the central nervous system (CNS). This study provides a comparative...
2.
Scardovi A, Bartolucci D, Montemurro L, Bortolotti S, Angelucci S, Amadesi C, et al.
Nucleic Acid Ther . 2024 Jul; 34(4):173-187. PMID: 38957973
Although has been considered an undruggable target, alterations confer poor prognosis in many pediatric and adult cancers. The novel -specific inhibitor BGA002 is an antigene peptide nucleic acid oligonucleotide covalently...
3.
Di Vito A, Mandrone M, Chiocchio I, Gorini F, Ravegnini G, Coschina E, et al.
Plants (Basel) . 2024 May; 13(9). PMID: 38732416
Novel treatments in gastrointestinal stromal tumors (GISTs) are essential due to imatinib resistance and the modest results obtained with multi-target tyrosine kinase inhibitors. We investigated the possibility that the hydroalcoholic...
4.
Ravegnini G, Gorini F, Coada C, De Leo A, de Biase D, Di Costanzo S, et al.
Cancer Sci . 2024 Jan; 115(3):883-893. PMID: 38196275
Endometrial cancer (EC) is the most prevalent gynecological cancer in high-income countries. Its incidence is skyrocketing due to the increase in risk factors such as obesity, which represents a true...
5.
Sita G, Graziosi A, Corrieri C, Ghelli L, Angelini S, Cortelli P, et al.
Int J Mol Sci . 2023 Nov; 24(22). PMID: 38003389
Alzheimer's disease (AD) represents the most frequent type of dementia worldwide, and aging is the most important risk factor for the sporadic form of the pathology. The endoplasmic reticulum (ER),...
6.
Gasperini S, Greco G, Angelini S, Hrelia P, Fimognari C, Lenzi M
Pharmaceutics . 2023 Oct; 15(10). PMID: 37896225
Mill. (Cs), a plant traditionally employed in nutrition and to treat various respiratory and gastrointestinal infections, possesses cancer chemopreventive characteristics. In particular, Cs bark extract previously demonstrated antiproliferative and pro-apoptotic...
7.
Coada C, Dondi G, Ravegnini G, Di Costanzo S, Tesei M, Fiuzzi E, et al.
J Gynecol Oncol . 2023 Sep; 34(6):e82. PMID: 37743060
Objective: Neoadjuvant chemotherapy (NACT) represents a treatment option in patients with advanced epithelial ovarian cancer (AEOC) who are not good candidates for primary debulking surgery. Usually, 3 cycles of chemotherapy...
8.
Lenzi M, Gasperini S, Corli G, Marti M, Hrelia P
Int J Mol Sci . 2023 Jul; 24(13). PMID: 37445675
MTTA, also known as mephtetramine, is a stimulant novel psychoactive substance characterized by a simil-cathinonic structure. To date, little has been studied on its pharmaco-toxicological profile, and its genotoxic potential...
9.
Di Vito A, Ravegnini G, Gorini F, Aasen T, Serrano C, Benuzzi E, et al.
Pharmacol Ther . 2023 Jun; 248:108475. PMID: 37302758
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal sarcomas and the gold-standard treatment is represented by tyrosine kinase inhibitors (TKIs). Unfortunately, first-line treatment with the TKI imatinib usually promotes partial response...
10.
Dothel G, Barbaro M, Di Vito A, Ravegnini G, Gorini F, Monesmith S, et al.
J Gastroenterol . 2023 May; 58(7):605-621. PMID: 37160449
Irritable bowel syndrome (IBS) is a complex multifactorial condition including alterations of the gut-brain axis, intestinal permeability, mucosal neuro-immune interactions, and microbiota imbalance. Recent advances proposed epigenetic factors as possible...