Patrik Ernfors
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Explore the profile of Patrik Ernfors including associated specialties, affiliations and a list of published articles.
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116
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7937
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Recent Articles
1.
Yu H, Nagi S, Usoskin D, Hu Y, Kupari J, Bouchatta O, et al.
Nat Neurosci
. 2024 Nov;
27(12):2326-2340.
PMID: 39496796
The versatility of somatosensation arises from heterogeneous dorsal root ganglion (DRG) neurons. However, soma transcriptomes of individual human (h)DRG neurons-critical information to decipher their functions-are lacking due to technical difficulties....
2.
Fatt M, Zhang M, Kupari J, Altinkok M, Yang Y, Hu Y, et al.
Science
. 2024 Aug;
385(6712):eado6593.
PMID: 39208104
Opioids are widely used, effective analgesics to manage severe acute and chronic pain, although they have recently come under scrutiny because of epidemic levels of abuse. While these compounds act...
3.
Ojeda-Alonso J, Calvo-Enrique L, Paricio-Montesinos R, Kumar R, Zhang M, Poulet J, et al.
Nat Commun
. 2024 Feb;
15(1):898.
PMID: 38320986
Previous work identified nociceptive Schwann cells that can initiate pain. Consistent with the existence of inherently mechanosensitive sensory Schwann cells, we found that in mice, the mechanosensory function of almost...
4.
Hu X, Buhl C, Sjogaard M, Schousboe K, Mizrak H, Kufaishi H, et al.
Diabetologia
. 2023 Sep;
66(12):2332-2345.
PMID: 37728731
Aims/hypothesis: Our aim was to investigate structural changes of cutaneous Schwann cells (SCs), including nociceptive Schwann cells (nSCs) and axons, in individuals with diabetic polyneuropathy. We also aimed to investigate...
5.
Yu H, Usoskin D, Nagi S, Hu Y, Kupari J, Bouchatta O, et al.
bioRxiv
. 2023 Mar;
PMID: 36993480
The versatility of somatosensation arises from heterogeneous dorsal root ganglion (DRG) neurons. However, soma transcriptomes of individual human DRG (hDRG) neurons-critical in-formation to decipher their functions-are lacking due to technical...
6.
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis
He Y, Ge C, Moreno-Giro A, Xu B, Beusch C, Sandor K, et al.
Nat Commun
. 2023 Feb;
14(1):691.
PMID: 36754962
Although elevated levels of anti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis (RA), the in vivo functions of these antibodies remain unclear. Here, we have expressed monoclonal ACPAs...
7.
8.
Hu X, Agarwal N, Zhang M, Ernfors P, Kuner R, Nyengaard J, et al.
J Chem Neuroanat
. 2022 Jun;
123:102118.
PMID: 35680105
Specialized cutaneous Schwann cells (SCs), termed nociceptive SCs, were recently discovered. Their function is not fully understood, but they are believed not only to support peripheral axons in mouse skin...
9.
Hu Y, Jiang Y, Behnan J, Ribeiro M, Kalantzi C, Zhang M, et al.
Sci Adv
. 2022 Jun;
8(23):eabm6340.
PMID: 35675414
Glioblastoma is believed to originate from nervous system cells; however, a putative origin from vessel-associated progenitor cells has not been considered. We deeply single-cell RNA-sequenced glioblastoma progenitor cells of 18...
10.
Muhl L, He L, Sun Y, Mae M, Pietila R, Liu J, et al.
Stem Cell Reports
. 2022 Apr;
17(5):1089-1104.
PMID: 35452595
Humanized mouse models and mouse-adapted SARS-CoV-2 virus are increasingly used to study COVID-19 pathogenesis, so it is important to learn where the SARS-CoV-2 receptor ACE2 is expressed. Here we mapped...