Patrick W McGrady
Overview
Explore the profile of Patrick W McGrady including associated specialties, affiliations and a list of published articles.
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7
Citations
966
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Recent Articles
1.
Bresler S, Weiser D, Huwe P, Park J, Krytska K, Ryles H, et al.
Cancer Cell
. 2014 Dec;
26(5):682-94.
PMID: 25517749
Genetic studies have established anaplastic lymphoma kinase (ALK), a cell surface receptor tyrosine kinase, as a tractable molecular target in neuroblastoma. We describe comprehensive genomic, biochemical, and computational analyses of...
2.
Nuchtern J, London W, Barnewolt C, Naranjo A, McGrady P, Geiger J, et al.
Ann Surg
. 2012 Sep;
256(4):573-80.
PMID: 22964741
Objective: To demonstrate that expectant observation of young infants with small adrenal masses would result in excellent event-free and overall survival. Background: Neuroblastoma is the most common malignant tumor in...
3.
Koyama H, Zhuang T, Light J, Kolla V, Higashi M, McGrady P, et al.
Clin Cancer Res
. 2012 Feb;
18(6):1588-97.
PMID: 22294723
Purpose: Neuroblastomas (NBs) have genomic, biological, and clinical heterogeneity. High-risk NBs are characterized by several genomic changes, including MYCN amplification and 1p36 deletion. We identified the chromatin-remodeling gene CHD5 as...
4.
Wang K, Diskin S, Zhang H, Attiyeh E, Winter C, Hou C, et al.
Nature
. 2010 Dec;
469(7329):216-20.
PMID: 21124317
Neuroblastoma is a childhood cancer of the sympathetic nervous system that accounts for approximately 10% of all paediatric oncology deaths. To identify genetic risk factors for neuroblastoma, we performed a...
5.
Bray I, Bryan K, Prenter S, Buckley P, Foley N, Murphy D, et al.
PLoS One
. 2009 Nov;
4(11):e7850.
PMID: 19924232
MiRNAs regulate gene expression at a post-transcriptional level and their dysregulation can play major roles in the pathogenesis of many different forms of cancer, including neuroblastoma, an often fatal paediatric...
6.
Diskin S, Hou C, Glessner J, Attiyeh E, Laudenslager M, Bosse K, et al.
Nature
. 2009 Jun;
459(7249):987-91.
PMID: 19536264
Common copy number variations (CNVs) represent a significant source of genetic diversity, yet their influence on phenotypic variability, including disease susceptibility, remains poorly understood. To address this problem in human...
7.
Attiyeh E, London W, Mosse Y, Wang Q, Winter C, Khazi D, et al.
N Engl J Med
. 2005 Nov;
353(21):2243-53.
PMID: 16306521
Background: Neuroblastoma is a childhood cancer with considerable morbidity and mortality. Tumor-derived biomarkers may improve risk stratification. Methods: We screened 915 samples of neuroblastoma for loss of heterozygosity (LOH) at...