Patrick W Keller
Overview
Explore the profile of Patrick W Keller including associated specialties, affiliations and a list of published articles.
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13
Citations
231
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Recent Articles
1.
Manders D, Kishore H, Gazdar A, Keller P, Tsunezumi J, Yanagisawa H, et al.
Oncotarget
. 2018 Mar;
9(18):14251-14267.
PMID: 29581841
Fibulin 5 (FBLN5) is an extracellular matrix glycoprotein that suppresses matrix metalloprotease 9 (MMP-9), angiogenesis and epithelial cell motility. Here, we investigated the regulation and function of in epithelial ovarian...
2.
Babayev S, Park C, Keller P, Carr B, Word R, Bukulmez O
Reprod Sci
. 2017 Sep;
24(10):1454-1461.
PMID: 28891417
Background: Androgenic compounds have been implicated in induction of endometrial atrophy yet the mechanisms of androgen effects on human endometrium have not been well studied. We hypothesized that androgens may...
3.
Maldonado P, Montoya T, Acevedo J, Keller P, Word R
Biol Reprod
. 2017 Apr;
96(1):81-92.
PMID: 28395337
Although the positive effects of vaginal estrogens and the selective estrogen receptor modulator, ospemifene (OS), on the vaginal epithelium are well recognized, less is known regarding the effects of these...
4.
Ripperda C, Maldonado P, Acevedo J, Keller P, Akgul Y, Shelton J, et al.
Menopause
. 2017 Feb;
24(7):838-849.
PMID: 28169915
Objective: Reconstructive surgery for pelvic organ prolapse is plagued with high failure rates possibly due to impaired healing or regeneration of the vaginal wall. Here, we tested the hypothesis that...
5.
Myogenic stem cell-laden hydrogel scaffold in wound healing of the disrupted external anal sphincter
Montoya T, Acevedo J, Smith B, Keller P, Sailors J, Tang L, et al.
Int Urogynecol J
. 2015 Feb;
26(6):893-904.
PMID: 25644049
Objective: To evaluate the effect of myogenic stem cell-laden hydrogel scaffold on contractile function and histomorphology of the external anal sphincter (EAS) after transection without repair. Methods: Eighty female rats...
6.
Mogami H, Keller P, Shi H, Word R
J Biol Chem
. 2014 Mar;
289(19):13295-307.
PMID: 24652285
Here, we investigated the effects of thrombin on matrix metalloproteinases (MMPs) and prostaglandin (PG) synthesis in fetal membranes. Thrombin activity was increased in human amnion from preterm deliveries. Treatment of...
7.
Balgobin S, Montoya T, Shi H, Acevedo J, Keller P, Riegel M, et al.
Biol Reprod
. 2013 Nov;
89(6):138.
PMID: 24174572
Loss of pelvic organ support (i.e., pelvic organ prolapse) is common in menopausal women. Surgical reconstruction of pelvic organ prolapse is plagued with high failure rates. The objective of this...
8.
Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R
J Biol Chem
. 2012 Nov;
288(3):1953-66.
PMID: 23184961
Fetal fibronectin (fFN) in cervical and vaginal secretions has been used as a predictor of preterm delivery. Here, we clarified the pathological function of fFN on cell type-specific matrix metalloproteinases...
9.
Pathi S, Acevedo J, Keller P, Kishore A, Miller R, Wai C, et al.
Obstet Gynecol
. 2011 Dec;
119(1):134-44.
PMID: 22183221
Objectives: To understand the endogenous process of wound healing after anal sphincter injury and to determine possible mechanisms by which mesenchymal stem cells (MSCs) exert their regenerative potential. Methods: Virginal...
10.
White A, Keller P, Acevedo J, Word R, Wai C
Obstet Gynecol
. 2010 Mar;
115(4):815-823.
PMID: 20308844
Objective: To estimate the effect of myogenic stem cells on contractile function of the external anal sphincter after transection with or without repair in an animal model. Methods: One hundred...