Patrick Sieber
Overview
Explore the profile of Patrick Sieber including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
980
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0
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Recent Articles
1.
Birker-Robaczewska M, Boucher M, Ranieri G, Poirey S, Studer R, Freti D, et al.
J Pharmacol Exp Ther
. 2025 Mar;
392(3):103396.
PMID: 40073729
Pulmonary fibrosis encompasses different chronic interstitial lung diseases, and the predominant form, idiopathic pulmonary fibrosis, remains to have a poor prognosis despite 2 approved therapies. Although the exact pathobiological mechanisms...
2.
Sieber P, Schafer A, Lieberherr R, Caimi S, Luthi U, Ryge J, et al.
JCI Insight
. 2022 Dec;
8(3).
PMID: 36520540
In the progression phase of idiopathic pulmonary fibrosis (IPF), the normal alveolar structure of the lung is lost and replaced by remodeled fibrotic tissue and by bronchiolized cystic airspaces. Although...
3.
Kawwass J, Ten Eyck P, Sieber P, Hipp H, Voorhis B
J Assist Reprod Genet
. 2021 Apr;
38(5):1171-1175.
PMID: 33797005
Purpose: To characterize national oocyte donation practice patterns from the perspective of individual donors rather than of recipients. Methods: Retrospective cohort including all donor oocyte retrievals and transfers reported to...
4.
Sieber P, Schafer A, Lieberherr R, Le Goff F, Stritt M, Welford R, et al.
PLoS One
. 2018 Nov;
13(11):e0207872.
PMID: 30485339
Pathological features of pulmonary fibrosis include accumulation of myofibroblasts and increased extracellular matrix (ECM) deposition in lung tissue. Contractile α-smooth muscle actin (α-SMA)-expressing myofibroblasts that produce and secrete ECM are...
5.
Welford R, Vercauteren M, Trebaul A, Cattaneo C, Eckert D, Garzotti M, et al.
Sci Rep
. 2016 Jul;
6:30059.
PMID: 27444653
The biogenic amine serotonin (5-HT) is a multi-faceted hormone that is synthesized from dietary tryptophan with the rate limiting step being catalyzed by the enzyme tryptophan hydroxylase (TPH). The therapeutic...
6.
Lescop C, Muller C, Mathys B, Birker M, de Kanter R, Kohl C, et al.
Eur J Med Chem
. 2016 Apr;
116:222-238.
PMID: 27061986
In a previous communication we reported on the discovery of alkylamino pyridine derivatives (e.g. 1) as a new class of potent, selective and efficacious S1P1 receptor (S1PR1) agonists. However, more...
7.
Bolli M, Lescop C, Birker M, de Kanter R, Hess P, Kohl C, et al.
Eur J Med Chem
. 2016 Mar;
115:326-41.
PMID: 27027817
In a previous communication we reported on the discovery of aminopyridine 1 as a potent, selective and orally active S1P1 receptor agonist. More detailed studies revealed that this compound is...
8.
Gillmor C, Roeder A, Sieber P, Somerville C, Lukowitz W
PLoS One
. 2016 Jan;
11(1):e0146492.
PMID: 26745275
Cytokinesis in plants involves the formation of unique cellular structures such as the phragmoplast and the cell plate, both of which are required to divide the cell after nuclear division....
9.
Sieber P, Wellmer F, Gheyselinck J, Riechmann J, Meyerowitz E
Development
. 2007 Feb;
134(6):1051-60.
PMID: 17287247
In plants, members of microRNA (miRNA) families are often predicted to target the same or overlapping sets of genes. It has thus been hypothesized that these miRNAs may act in...
10.
Heisler M, Ohno C, Das P, Sieber P, Reddy G, Long J, et al.
Curr Biol
. 2005 Nov;
15(21):1899-911.
PMID: 16271866
Background: Plants produce leaf and flower primordia from a specialized tissue called the shoot apical meristem (SAM). Genetic studies have identified a large number of genes that affect various aspects...