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Patrick Roche

Explore the profile of Patrick Roche including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 574
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Recent Articles
1.
Fitzhenry C, Jowett L, Roche P, Harrington K, Moore B, Paull B, et al.
J Chromatogr A . 2021 Jul; 1652:462368. PMID: 34246962
A portable and automated IC system with a dual-capability for the analysis of both fresh and saline environmental waters has been developed. Detection of nitrate in complex matrices such as...
2.
Murray E, Roche P, Briet M, Moore B, Morrin A, Diamond D, et al.
Talanta . 2020 May; 216:120955. PMID: 32456896
A cost-effective, automated and portable IC has been developed for in-situ analysis of nitrite and nitrate in natural waters. The system employed 3D printed pumps for eluent delivery and a...
3.
deLemos A, Patel M, Gawrieh S, Burney H, Dakhoul L, Miller E, et al.
Clin Transl Gastroenterol . 2020 May; 11(3):e00139. PMID: 32352723
Introduction: The burden of hepatocellular carcinoma (HCC) occurring in patients with alcoholic liver disease (ALD) is increasing at an alarming rate. The aims of this study were to compare the...
4.
Murray E, Roche P, Harrington K, McCaul M, Moore B, Morrin A, et al.
J Chromatogr A . 2019 Jun; 1603:8-14. PMID: 31151694
A low cost, UV absorbance detector incorporating a 235 nm light emitting diode (LED) for portable ion chromatography has been designed and fabricated to achieve rapid, selective detection of nitrite...
5.
Papouchado B, Myles J, Lloyd R, Stoler M, Oliveira A, Downs-Kelly E, et al.
Am J Surg Pathol . 2010 Apr; 34(6):767-76. PMID: 20421783
The importance of HER2 status in breast cancer management has focused attention on the ability of clinical assays to correctly assign HER2 amplification status. There is no consensus as to...
6.
Bilous M, Osamura R, Ruschoff J, Van de Vijver M, Hanna W, Penault-Llorca F, et al.
Hum Pathol . 2009 Nov; 41(2):304-5. PMID: 19914678
No abstract available.
7.
Tubbs R, Pettay J, Barry T, Swain E, Loftus M, Cook J, et al.
J Mol Histol . 2006 Nov; 38(2):159-65. PMID: 17094016
Implementation of interphase fluorescence in situ hybridization (FISH) assays in the clinical laboratory requires validation against established methods. Validation tools in common use include exchange of consecutive sections with another...
8.
Collignon F, Wetjen N, Cohen-Gadol A, Cascino G, Parisi J, Meyer F, et al.
J Neurosurg . 2006 Jul; 105(1):77-87. PMID: 16874892
Object: The causes of epileptic events remain unclear. Much in vitro and in vivo experimental evidence suggests that gap junctions formed by connexins (Cxs) between neurons and/or astrocytes contribute to...
9.
Tubbs R, Pettay J, Powell R, Hicks D, Roche P, Powell W, et al.
Appl Immunohistochem Mol Morphol . 2005 Nov; 13(4):371-5. PMID: 16280669
Ultrasensitive bright field in situ hybridization assays using enzyme metallography (EnzMet) have been developed and validated, but little is known regarding the applicability of EnzMet for immunophenotypic detection of protein...
10.
Downs-Kelly E, Pettay J, Hicks D, Skacel M, Yoder B, Rybicki L, et al.
Am J Surg Pathol . 2005 Oct; 29(11):1505-11. PMID: 16224218
Fluorescence in situ hybridization (FISH) has both excellent sensitivity and specificity in detecting HER2 gene amplification in invasive breast carcinoma. FISH has not been widely implemented in clinical practice because...