Patrick R Secor
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Explore the profile of Patrick R Secor including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
1728
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Recent Articles
1.
Fitzpatrick A, Taylor V, Patel P, Faith D, Secor P, Maxwell K
mBio
. 2025 Feb;
16(3):e0246624.
PMID: 39918338
Phages have been shown to use diverse strategies to commandeer bacterial host cell metabolism during infection. However, for many of the physiological changes in bacteria during infection, it is often...
2.
Pourtois J, Haddock N, Gupta A, Khosravi A, Martinez H, Schmidt A, et al.
bioRxiv
. 2025 Jan;
PMID: 39868244
Pf bacteriophages, lysogenic viruses that infect , are implicated in the pathogenesis of chronic infections; phage-infected (Pf+) strains are known to predominate in people with cystic fibrosis (pwCF) who are...
3.
Burgener E, Gupta A, Nakano K, Gibbs S, Sommers M, Khosravi A, et al.
J Cyst Fibros
. 2024 Nov;
PMID: 39490215
Background: The Pseudomonas filamentous bacteriophage (Pf) infects Pseudomonas aeruginosa (Pa) and is abundant in the airways of many people with cystic fibrosis (CF) (pwCF). We previously demonstrated that Pf promotes...
4.
Burgener E, Cai P, Kratochvil M, Rojas-Hernandez L, Joo N, Gupta A, et al.
PNAS Nexus
. 2024 Sep;
3(9):pgae390.
PMID: 39301510
is a major pulmonary pathogen causing chronic pulmonary infections in people with cystic fibrosis (CF). The and lysogenic bacteriophage, Pf phage, is abundant in the airways of many people with...
5.
Chen Q, Cai P, Chang T, Burgener E, Kratochvil M, Gupta A, et al.
Sci Adv
. 2024 May;
10(22):eadl5576.
PMID: 38820163
Despite great progress in the field, chronic () infections remain a major cause of mortality in patients with cystic fibrosis (pwCF), necessitating treatment with antibiotics. Pf is a filamentous bacteriophage...
6.
Schmidt A, Schwartzkopf C, Pourtois J, Burgener E, Faith D, Joyce A, et al.
J Bacteriol
. 2024 Apr;
206(5):e0040223.
PMID: 38687034
is an opportunistic bacterial pathogen that commonly causes medical hardware, wound, and respiratory infections. Temperate filamentous Pf phages that infect impact numerous virulence phenotypes. Most work on Pf phages has...
7.
Copeland C, Roddy J, Schmidt A, Secor P, Wheeler T
NAR Genom Bioinform
. 2024 Apr;
6(2):lqae030.
PMID: 38584872
Bacteriophages are viruses that infect bacteria. Many bacteriophages integrate their genomes into the bacterial chromosome and become prophages. Prophages may substantially burden or benefit host bacteria fitness, acting in some...
8.
Faith D, Kinnersley M, Brooks D, Drecktrah D, Hall L, Luo E, et al.
PLoS Pathog
. 2024 Apr;
20(4):e1012122.
PMID: 38558079
Lyme disease is a tick-borne infection caused by the spirochete Borrelia (Borreliella) burgdorferi. Borrelia species have highly fragmented genomes composed of a linear chromosome and a constellation of linear and...
9.
Chen Q, Cai P, Chang T, Burgener E, Kratochvil M, Gupta A, et al.
bioRxiv
. 2024 Mar;
PMID: 38496625
Despite great progress in the field, chronic () infections remain a major cause of morbidity and mortality in patients with cystic fibrosis, necessitating treatment with inhaled antibiotics. Pf phage is...
10.
Roman-Cruz V, Miller S, Schoener R, Lukasiewicz C, Schmidt A, DeBuysscher B, et al.
Vaccines (Basel)
. 2024 Feb;
12(2).
PMID: 38400099
(), a WHO priority 1 pathogen, resulted in approximately 559,000 deaths globally in 2019. has a multitude of host-immune evasion strategies that enhance virulence. Most clinical isolates of are infected...