Patrick Quint
Overview
Explore the profile of Patrick Quint including associated specialties, affiliations and a list of published articles.
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11
Citations
271
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Recent Articles
1.
Royal V, Quint P, LeBlanc M, LeBlanc R, Duncanson G, Perrizo R, et al.
J Am Soc Nephrol
. 2014 Sep;
26(4):784-90.
PMID: 25194005
Monoclonal Ig deposition disease (MIDD) is a rare complication of monoclonal gammopathy characterized by deposition of monoclonal Ig light chains and/or heavy chains along the glomerular and tubular basement membranes....
2.
Ota K, Quint P, Weivoda M, Ruan M, Pederson L, Westendorf J, et al.
Bone
. 2013 Jul;
57(1):68-75.
PMID: 23891907
The processes of bone resorption and bone formation are tightly coupled in young adults, which is crucial to maintenance of bone integrity. We have documented that osteoclasts secrete chemotactic agents...
3.
Ota K, Quint P, Ruan M, Pederson L, Westendorf J, Khosla S, et al.
Endocrinology
. 2013 Jul;
154(10):3745-52.
PMID: 23861379
In young adults, bone lost through osteoclast-mediated resorption is precisely replaced in both location and amount. Understanding how these two processes are coupled is crucial to advancing treatments for osteoporosis,...
4.
DSouza A, Theis J, Quint P, Kyle R, Gertz M, Zeldenrust S, et al.
Am J Hematol
. 2013 Apr;
88(7):577-80.
PMID: 23606017
Amyloidosis affecting lymph nodes (LN) may occur in the setting of systemic amyloidosis or as an entity localized to the site of production (peritumoral). Why some LN amyloid remains peritumoral...
5.
Ota K, Quint P, Ruan M, Pederson L, Westendorf J, Khosla S, et al.
J Cell Biochem
. 2013 Mar;
114(8):1901-1907.
PMID: 23494985
Osteoclast-mediated bone resorption precedes osteoblast-mediated bone formation through early adulthood, but formation fails to keep pace with resorption during aging. We previously identified several factors produced by osteoclasts that promote...
6.
Sethi S, Theis J, Vrana J, Fervenza F, Sethi A, Qian Q, et al.
Clin J Am Soc Nephrol
. 2013 Feb;
8(6):915-21.
PMID: 23411427
Background And Objectives: Organized deposits are present in amyloidosis, fibrillary GN, and immunotactoid glomerulopathy. However, the constituents of the deposits are not known. Design, Setting, Participants, & Measurements: Laser microdissection...
7.
Quint P, Ruan M, Pederson L, Kassem M, Westendorf J, Khosla S, et al.
J Biol Chem
. 2013 Jan;
288(8):5398-406.
PMID: 23300082
Normal bone turnover requires tight coupling of bone resorption and bone formation to preserve bone quantity and structure. With aging and during several pathological conditions, this coupling breaks down, leading...
8.
Sethi S, Theis J, Quint P, Maierhofer W, Kurtin P, Dogan A, et al.
Am J Kidney Dis
. 2012 Sep;
61(1):161-6.
PMID: 22938848
We present a case of a 75-year-old woman who presented with progressive kidney failure. Kidney biopsy performed to determine the cause of kidney failure showed amyloidosis of undetermined type. Laser...
9.
Quint P, Ayala I, Busby S, Chalmers M, Griffin P, Rocca J, et al.
Biochemistry
. 2006 Jul;
45(27):8209-15.
PMID: 16819819
Human manganese superoxide dismutase (MnSOD) is a homotetramer of 22 kDa subunits, a dimer of dimers containing dimeric and tetrameric interfaces. We have investigated conformational mobility at these interfaces by...
10.
Quint P, Reutzel R, Mikulski R, McKenna R, Silverman D
Free Radic Biol Med
. 2006 Jan;
40(3):453-8.
PMID: 16443160
A cellular consequence of the reaction of superoxide and nitric oxide is enhanced peroxynitrite levels. Reaction of peroxynitrite with manganese superoxide dismutase (MnSOD) causes nitration of the active-site residue Tyr34...