Patrick McMillen
Overview
Explore the profile of Patrick McMillen including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
136
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Recent Articles
1.
McMillen P, Levin M
Commun Biol
. 2024 Mar;
7(1):378.
PMID: 38548821
A defining feature of biology is the use of a multiscale architecture, ranging from molecular networks to cells, tissues, organs, whole bodies, and swarms. Crucially however, biology is not only...
2.
Tung A, Sperry M, Clawson W, Pavuluri A, Bulatao S, Yue M, et al.
Nat Commun
. 2024 Jan;
15(1):535.
PMID: 38233424
Information for organismal patterning can come from a variety of sources. We investigate the possibility that instructive influences for normal embryonic development are provided not only at the level of...
3.
McMillen P, Levin M
Methods Mol Biol
. 2023 Dec;
2745:91-102.
PMID: 38060181
Fluorescent lifetime imaging (FLIM) is a powerful tool for visualizing physiological parameters in vivo. We present here a 3-dye strategy for mapping bioelectric patterns in living Xenopus laevis embryos leveraging...
4.
Grodstein J, McMillen P, Levin M
Front Cell Dev Biol
. 2023 Aug;
11:1087650.
PMID: 37645245
Morphogenesis, the establishment and repair of emergent complex anatomy by groups of cells, is a fascinating and biomedically-relevant problem. One of its most fascinating aspects is that a developing embryo...
5.
The Yin and Yang of Breast Cancer: Ion Channels as Determinants of Left-Right Functional Differences
Masuelli S, Real S, McMillen P, Oudin M, Levin M, Roque M
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37446299
Breast cancer is a complex and heterogeneous disease that displays diverse molecular subtypes and clinical outcomes. Although it is known that the location of tumors can affect their biological behavior,...
6.
McMillen P, Walker S, Levin M
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36076979
There is a growing appreciation in the fields of cell biology and developmental biology that cells collectively process information in time and space. While many powerful molecular tools exist to...
7.
McMillen P, Oudin M, Levin M, Payne S
Front Cell Dev Biol
. 2021 Oct;
9:739024.
PMID: 34621752
Cellular communication is important in all aspects of tissue and organism functioning, from the level of single cells, two discreet populations, and distant tissues of the body. Long distance communication...
8.
McMillen P, Novak R, Levin M
J Mol Biol
. 2019 Nov;
432(2):605-620.
PMID: 31711960
Although chemical signaling during embryogenesis is readily addressed by a plethora of available techniques, the developmental functions of ionic signaling are still poorly understood. It is increasingly realized that bioelectric...
9.
McMillen P, Chatti V, Julich D, Holley S
Curr Biol
. 2016 Feb;
26(4):542-9.
PMID: 26853361
Differential cadherin (Cdh) expression is a classical mechanism for in vitro cell sorting. Studies have explored the roles of differential Cdh levels in cell aggregates and during vertebrate gastrulation, but...
10.
McMillen P, Holley S
Curr Opin Cell Biol
. 2015 Jul;
36:48-53.
PMID: 26189063
In this review, we highlight recent re-evaluations of the classical cell sorting models and their application to understanding embryonic morphogenesis. Modern genetic and biophysical techniques reveal that tissue self-assembly is...