Patrick M Schurch
Overview
Explore the profile of Patrick M Schurch including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
6
Citations
30
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pascual-Pasto G, McIntyre B, Hines M, Giudice A, Garcia-Gerique L, Hoffmann J, et al.
Nat Commun
. 2024 Aug;
15(1):7141.
PMID: 39164224
Novel chimeric antigen receptor (CAR) T-cell approaches are needed to improve therapeutic efficacy in solid tumors. High-risk neuroblastoma is an aggressive pediatric solid tumor that expresses cell-surface GPC2 and GD2...
2.
Losa M, Emmenegger M, De Rossi P, Schurch P, Serdiuk T, Pengo N, et al.
EMBO Mol Med
. 2024 Jul;
16(9):2024-2042.
PMID: 39080493
Extracellularly released molecular inflammasome assemblies -ASC specks- cross-seed Aβ amyloid in Alzheimer's disease. Here we show that ASC governs the extent of inflammation-induced amyloid A (AA) amyloidosis, a systemic disease...
3.
Wildschut M, Mena J, Dordelmann C, van Oostrum M, Hale B, Settelmeier J, et al.
Nat Commun
. 2023 Oct;
14(1):6414.
PMID: 37828014
Myelofibrosis is a hematopoietic stem cell disorder belonging to the myeloproliferative neoplasms. Myelofibrosis patients frequently carry driver mutations in either JAK2 or Calreticulin (CALR) and have limited therapeutic options. Here,...
4.
Lysenko V, Schurch P, Tuzlak S, van Wijk N, Kovtonyuk L, Becher B, et al.
Leukemia
. 2023 Apr;
37(6):1277-1286.
PMID: 37095207
Polycythemia vera (PV) is a hematopoietic stem cell neoplasm driven by somatic mutations in JAK2, leading to increased red blood cell (RBC) production uncoupled from mechanisms that regulate physiological erythropoiesis....
5.
Schurch P, Malinovska L, Hleihil M, Losa M, Hofstetter M, Wildschut M, et al.
Cell Rep
. 2022 Nov;
41(8):111689.
PMID: 36417879
Calreticulin (CALR) is an endoplasmic reticulum (ER)-retained chaperone that assists glycoproteins in obtaining their structure. CALR mutations occur in patients with myeloproliferative neoplasms (MPNs), and the ER retention of CALR...
6.
Bosse K, Giudice A, Lane M, McIntyre B, Schurch P, Pascual-Pasto G, et al.
Cancer Discov
. 2022 Sep;
12(12):2800-2819.
PMID: 36108156
Significance: ctDNA is prevalent in children with neuroblastoma. Serial ctDNA profiling in patients with neuroblastoma improves the detection of potentially clinically actionable and functionally relevant variants in cancer driver genes...