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Patrick M Schlievert

Explore the profile of Patrick M Schlievert including associated specialties, affiliations and a list of published articles. Areas
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Articles 164
Citations 5102
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Recent Articles
1.
Kenney H, Yoshida T, Berdyshev E, Calatroni A, Gill S, Simpson E, et al.
J Allergy Clin Immunol . 2024 Sep; 155(2):479-490. PMID: 39343173
Background: Atopic dermatitis (AD) is an inflammatory skin condition characterized by widely variable cutaneous Staphylococcus aureus abundance that contributes to disease severity and rapidly responds to type 2 immune blockade...
2.
Wilkie H, Das M, Pelovitz T, Bainter W, Woods B, Alasharee M, et al.
J Allergy Clin Immunol . 2024 Jan; 154(1):143-156. PMID: 38185418
Background: Dedicator of cytokinesis 8 (DOCK8)-deficient patients have severe eczema, elevated IgE, and eosinophilia, features of atopic dermatitis (AD). Objective: We sought to understand the mechanisms of eczema in DOCK8...
3.
Upton E, Schlievert P, Zhang Y, Rauckhorst A, Taylor E, Radoshevich L
MicroPubl Biol . 2023 Nov; 2023. PMID: 37954520
Glycerol Monolaurate (GML) is a naturally occurring fatty acid monoester with antimicrobial properties. is an agent of bioterrorism known for its unique lipopolysaccharide structure and low immunogenicity. Here we assessed...
4.
Schlievert P, Nelson J, Kilgore S, Radoshevich L, Klingelhutz A, Leung D
Microbiol Spectr . 2023 Nov; 11(6):e0289823. PMID: 37937984
causes a myriad of human diseases, ranging from relatively mild soft tissue infections to highly fatal pneumonia, sepsis, and toxic shock syndrome. The organisms primarily cause diseases across mucosal and...
5.
Moran M, Brewer M, Schlievert P, Beck L
Microbiol Spectr . 2023 Sep; :e0168423. PMID: 37737609
Individuals with atopic dermatitis (AD) are highly colonized by and are more susceptible to severe viral complications. We hypothesized that secreted virulence factors may alter keratinocyte biology to enhance viral...
6.
Schlievert P, Gaitan A, Kilgore S, Roe A, Maukonen J, Lehtoranta L, et al.
Microbiol Spectr . 2023 Jul; 11(4):e0173523. PMID: 37404182
Staphylococcus aureus is a human pathogen with many infections originating on mucosal surfaces. One common group of S. aureus is the USA200 (CC30) clonal group, which produces toxic shock syndrome...
7.
Simpson E, Schlievert P, Yoshida T, Lussier S, Boguniewicz M, Hata T, et al.
J Allergy Clin Immunol . 2023 Jun; 152(5):1179-1195. PMID: 37315812
Background: Atopic dermatitis (AD) is an inflammatory disorder characterized by dominant type 2 inflammation leading to chronic pruritic skin lesions, allergic comorbidities, and Staphylococcus aureus skin colonization and infections. S...
8.
Pomputius W, Kilgore S, Schlievert P
BMC Pediatr . 2023 Mar; 23(1):108. PMID: 36882717
Background: We describe a case of a toxic shock-like syndrome in a child, which was associated with Staphylococcus epidermidis instead of Staphylococcus aureus or Streptococcus pyogenes, the usual causes of...
9.
Schlievert P
Microbiol Spectr . 2023 Feb; :e0444622. PMID: 36815779
Three mutants individually of both staphylococcal enterotoxins B and C were prepared by site-specific mutagenesis of enterotoxin amino acids that contact host T lymphocyte immune cell receptor sites (N23A, Q210A,...
10.
Schlievert P, Kilgore S, Beck L, Yoshida T, Klingelhutz A, Leung D
mSphere . 2023 Jan; 8(1):e0057622. PMID: 36598227
Innate immune molecules, including antimicrobial peptides (for example, defensins) and lysozyme, function to delay or prevent bacterial infections. These molecules are commonly found on mucosal and skin surfaces. Staphylococcus aureus...