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Patrick Linder

Explore the profile of Patrick Linder including associated specialties, affiliations and a list of published articles. Areas
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Articles 54
Citations 3344
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Recent Articles
1.
Guimaraes V, Le Scornet A, Khemici V, Hausmann S, Armitano J, Prados J, et al.
Front Microbiol . 2021 May; 12:586886. PMID: 34017314
Plasmids need to ensure their transmission to both daughter-cells when their host divides, but should at the same time avoid overtaxing their hosts by directing excessive host-resources toward production of...
2.
Valentini M, Linder P
Methods Mol Biol . 2020 Nov; 2209:17-34. PMID: 33201460
RNA helicases are ubiquitous, highly conserved RNA-binding enzymes that use the energy derived from the hydrolysis of nucleoside triphosphate to modify the structure of RNA molecules and/or the functionality of...
3.
Khemici V, Prados J, Petrignani B, Di Nolfi B, Berge E, Manzano C, et al.
PLoS Genet . 2020 Jul; 16(7):e1008779. PMID: 32730248
Staphylococcus aureus is an opportunistic pathogen that can grow in a wide array of conditions: on abiotic surfaces, on the skin, in the nose, in planktonic or biofilm forms and...
4.
Trachsel E, Redder P, Linder P, Armitano J
PLoS Genet . 2019 Aug; 15(8):e1008336. PMID: 31415562
Magnesium is one of the most abundant metal ions in living cells. Very specific and devoted transporters have evolved for transporting Mg2+ ions across the membrane and maintain magnesium homeostasis....
5.
Khemici V, Linder P
Biochem Soc Trans . 2018 Jan; 46(1):163-172. PMID: 29351962
RNA molecules have the tendency to fold into complex structures or to associate with complementary RNAs that exoribonucleases have difficulties processing or degrading. Therefore, degradosomes in bacteria and organelles as...
6.
Linder P, Armitano J
Swiss Med Wkly . 2017 Nov; 147:w14527. PMID: 29120018
The opportunistic pathogen Staphylococcus aureus encounters a variety of host defence systems depending on its localisation during colonisation in the nares, systemic infections within the body, or persistent infections within...
7.
Hausmann S, Guimaraes V, Garcin D, Baumann N, Linder P, Redder P
RNA Biol . 2017 Mar; 14(10):1431-1443. PMID: 28277929
RNA decay and RNA maturation are important steps in the regulation of bacterial gene expression. RNase J, which is present in about half of bacterial species, has been shown to...
8.
Buvelot H, Posfay-Barbe K, Linder P, Schrenzel J, Krause K
FEMS Microbiol Rev . 2016 Dec; 41(2):139-157. PMID: 27965320
Dysfunction of phagocytes is a relevant risk factor for staphylococcal infection. The most common hereditary phagocyte dysfunction is chronic granulomatous disease (CGD), characterized by impaired generation of reactive oxygen species...
9.
Armitano J, Redder P, Guimaraes V, Linder P
Front Microbiol . 2016 Dec; 7:1888. PMID: 27933050
Internal bacterial concentration of Mg, the most abundant divalent cation in living cells, is estimated to be in the single millimolar range. However, many bacteria will thrive in media with...
10.
Prados J, Linder P, Redder P
BMC Genomics . 2016 Nov; 17(1):849. PMID: 27806702
Background: Bacteria rely on efficient gene regulatory mechanisms to switch between genetic programs when they are facing new environments. Although this regulation can occur at many different levels, one of...