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Patrick Kaifosh

Explore the profile of Patrick Kaifosh including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 1144
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Recent Articles
1.
Danielson N, Zaremba J, Kaifosh P, Bowler J, Ladow M, Losonczy A
Neuron . 2016 Jul; 91(3):652-65. PMID: 27397517
The mammalian hippocampus is critical for spatial information processing and episodic memory. Its primary output cells, CA1 pyramidal cells (CA1 PCs), vary in genetics, morphology, connectivity, and electrophysiological properties. It...
2.
Kaifosh P, Losonczy A
Neuron . 2016 May; 90(3):622-34. PMID: 27146266
We present a model for neural circuit mechanisms underlying hippocampal memory. Central to this model are nonlinear interactions between anatomically and functionally segregated inputs onto dendrites of pyramidal cells in...
3.
Danielson N, Kaifosh P, Zaremba J, Lovett-Barron M, Tsai J, Denny C, et al.
Neuron . 2016 Mar; 90(1):101-12. PMID: 26971949
Adult-born granule cells (abGCs) have been implicated in cognition and mood; however, it remains unknown how these cells behave in vivo. Here, we have used two-photon calcium imaging to monitor...
4.
Requarth T, Kaifosh P, Sawtell N
J Neurosci . 2014 Nov; 34(48):16103-16. PMID: 25429151
Animals must distinguish behaviorally relevant patterns of sensory stimulation from those that are attributable to their own movements. In principle, this distinction could be made based on internal signals related...
5.
Kaifosh P, Zaremba J, Danielson N, Losonczy A
Front Neuroinform . 2014 Oct; 8:80. PMID: 25295002
Fluorescence imaging is a powerful method for monitoring dynamic signals in the nervous system. However, analysis of dynamic fluorescence imaging data remains burdensome, in part due to the shortage of...
6.
Kaifosh P, Losonczy A
Neuron . 2014 Sep; 83(6):1231-4. PMID: 25233301
Whether morphology tailors functional properties of pyramidal neurons is not completely understood. In this issue of Neuron, Thome et al. (2014) show that, in hippocampal pyramidal neurons, axons frequently originate...
7.
Lovett-Barron M, Kaifosh P, Kheirbek M, Danielson N, Zaremba J, Reardon T, et al.
Science . 2014 Feb; 343(6173):857-63. PMID: 24558155
Fear memories guide adaptive behavior in contexts associated with aversive events. The hippocampus forms a neural representation of the context that predicts aversive events. Representations of context incorporate multisensory features...
8.
Kennedy A, Wayne G, Kaifosh P, Alvina K, Abbott L, Sawtell N
Nat Neurosci . 2014 Feb; 17(3):416-22. PMID: 24531306
Mormyrid electric fish are a model system for understanding how neural circuits predict the sensory consequences of motor acts. Medium ganglion cells in the electrosensory lobe create negative images that...
9.
Kaifosh P, Lovett-Barron M, Turi G, Reardon T, Losonczy A
Nat Neurosci . 2013 Aug; 16(9):1182-4. PMID: 23912949
Hippocampal interneurons receive GABAergic input from the medial septum. Using two-photon Ca(2+) imaging of axonal boutons in hippocampal CA1 of behaving mice, we found that populations of septo-hippocampal GABAergic boutons...
10.
Lovett-Barron M, Turi G, Kaifosh P, Lee P, Bolze F, Sun X, et al.
Nat Neurosci . 2012 Jan; 15(3):423-30, S1-3. PMID: 22246433
Transforming synaptic input into action potential output is a fundamental function of neurons. The pattern of action potential output from principal cells of the mammalian hippocampus encodes spatial and nonspatial...