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Patrick J Blatchford

Explore the profile of Patrick J Blatchford including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 1006
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Recent Articles
1.
Lentz R, Friedrich T, Blatchford P, Jordan K, Pitts T, Robinson H, et al.
Clin Cancer Res . 2024 Jun; 30(17):3768-3778. PMID: 38869830
Purpose: In this single-institution phase II investigator-initiated study, we assessed the ability of MAPK and VEGF pathway blockade to overcome resistance to immunotherapy in microsatellite-stable metastatic colorectal cancer (MSS mCRC)....
2.
Scott A, Basu Mallick A, Dotan E, Cohen S, Gold P, Hochster H, et al.
Cancer Res Commun . 2023 Mar; 2(10):1188-1196. PMID: 36969746
Purpose: Multi-tyrosine kinase inhibitors (TKI) have shown clinical activity in patients with metastatic colorectal cancer. Cabozantinib, a multi-TKI, exhibited potent antitumor activity superior to regorafenib in preclinical colorectal cancer patient-derived...
3.
Lang J, Leal A, Marin-Jimenez J, Hartman S, Shulman J, Navarro N, et al.
Front Oncol . 2022 Nov; 12:877635. PMID: 36419897
Immune checkpoint inhibitors have been found to be effective in metastatic MSI-high colorectal cancers (CRC), however, have no efficacy in microsatellite stable (MSS) cancers, which comprise the majority of mCRC...
4.
Wherry S, Blatchford P, Swanson C, Wellington T, Boxer R, Kohrt W
Bone . 2021 Jul; 153:116108. PMID: 34252605
Background: Endurance exercise can cause a decrease in serum ionized calcium (iCa) and increases in parathyroid hormone (PTH) and bone resorption, reflected by serum carboxy-terminal collagen crosslinks (CTX). We developed...
5.
Marin-Jimenez J, Capasso A, Lewis M, Bagby S, Hartman S, Shulman J, et al.
Front Immunol . 2021 Apr; 12:607282. PMID: 33854497
Over the past decade, immunotherapies have revolutionized the treatment of cancer. Although the success of immunotherapy is remarkable, it is still limited to a subset of patients. More than 1500...
6.
Hu J, Blatchford P, Goldenberg N, Kittelson J
Stat Med . 2020 Oct; 39(26):3823-3839. PMID: 33048360
Although all clinical trials are designed and monitored using more than one endpoint, methods are needed to assure that decision criteria are chosen to reflect the clinically relevant tradeoffs that...
7.
Miller M, Cook P, Magnusson D, Morris M, Blatchford P, Schenkman M, et al.
PM R . 2020 Sep; 13(5):453-460. PMID: 32926546
Background: Interventions targeting psychosocial factors may improve rehabilitation outcomes for prosthesis users after lower-limb amputation (LLA), but there is a need to identify targeted factors for minimizing disability. Objective: To...
8.
Pate A, Lowery J, Kilbourn K, Blatchford P, McNulty M, Risendal B
J Cancer Surviv . 2020 May; 14(5):653-659. PMID: 32394045
Purpose: Colorectal cancer (CRC) is the third most common cancer in the USA. The objective of this study was to compare quality of life (QoL) across long-term colorectal cancer survivors...
9.
Christiansen C, Miller M, Kline P, Fields T, Sullivan W, Blatchford P, et al.
PM R . 2020 Apr; 12(10):957-966. PMID: 32248638
Background: Lower-limb amputation (LLA) due to non-traumatic vascular etiology is linked to extremely low physical activity and high disability. Objective: To test the feasibility of a biobehavioral intervention designed to...
10.
Ozemek C, Hildreth K, Blatchford P, Hurt K, Bok R, Seals D, et al.
J Appl Physiol (1985) . 2020 Mar; 128(4):739-747. PMID: 32134713
Regular exercise enhances endothelial function in older men, but not consistently in estrogen-deficient postmenopausal women. Estradiol treatment improves basal endothelial function and restores improvements in endothelial function (flow-mediated dilation, FMD)...