Patrick J Atkinson
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Explore the profile of Patrick J Atkinson including associated specialties, affiliations and a list of published articles.
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30
Citations
441
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Recent Articles
1.
Bravo D, Vaidyanathan S, Baker J, Sinha V, Tsai E, Roozdar P, et al.
bioRxiv
. 2025 Feb;
PMID: 39896581
Modulator agents that restore cystic fibrosis transmembrane conductance regulator (CFTR) function have revolutionized outcomes in cystic fibrosis, an incurable multisystem disease. Barriers exist to modulator use, making local CFTR gene...
2.
Hein D, Srivastava A, Willson S, Telehowski P, Atkinson P, Atkinson T
Arthroplast Today
. 2025 Jan;
31():101599.
PMID: 39835248
Background: Reducing unnecessary emergency department (ED) visits following joint arthroplasty is an important goal. Literature suggests 30-day visit rates range between 4% and 15%, with only 20%-25% of these admitted...
3.
Chiot A, Felgner M, Brownell D, Rott K, Bogachuk A, Rosmus D, et al.
bioRxiv
. 2024 Nov;
PMID: 39554030
Recent advances in fate mapping and single-cell technologies have revealed how the dynamics and function of tissue-resident macrophages are shaped by their environment. However, macrophages in sensory organs such as...
4.
Wang T, Ling A, Billings S, Hosseini D, Vaisbuch Y, Kim G, et al.
Nat Commun
. 2024 Jun;
15(1):4833.
PMID: 38844821
Mammalian inner ear hair cell loss leads to permanent hearing and balance dysfunction. In contrast to the cochlea, vestibular hair cells of the murine utricle have some regenerative capacity. Whether...
5.
Udagawa T, Takahashi E, Tatsumi N, Mutai H, Saijo H, Kondo Y, et al.
Sci Rep
. 2024 Jan;
14(1):2210.
PMID: 38278860
Cochlear melanocytes are intermediate cells in the stria vascularis that generate endocochlear potentials required for auditory function. Human PAX3 mutations cause Waardenburg syndrome and abnormalities of skin and retinal melanocytes,...
6.
Aaron K, Pekrun K, Atkinson P, Billings S, Abitbol J, Lee I, et al.
Mol Ther Methods Clin Dev
. 2023 Sep;
30:413-428.
PMID: 37663645
Adeno-associated virus (AAV)-mediated gene transfer has shown promise in rescuing mouse models of genetic hearing loss, but how viral capsid and promoter selection affects efficacy is poorly characterized. Here, we...
7.
Udagawa T, Takahashi E, Tatsumi N, Mutai H, Kondo Y, Atkinson P, et al.
Res Sq
. 2023 Jun;
PMID: 37333245
Cochlear melanocytes are intermediate cells in the stria vascularis that generate endocochlear potentials required for auditory function. Human PAX3 mutations cause Waardenburg syndrome and abnormalities of melanocytes, manifested as congenital...
8.
Xia A, Udagawa T, Quinones P, Atkinson P, Applegate B, Cheng A, et al.
J Neurophysiol
. 2022 Oct;
128(5):1365-1373.
PMID: 36259670
The mammalian cochlea contains three rows of outer hair cells (OHCs) that amplify the basilar membrane traveling wave with high gain and exquisite tuning. The pattern of OHC loss caused...
9.
Udagawa T, Atkinson P, Milon B, Abitbol J, Song Y, Sperber M, et al.
PLoS Biol
. 2021 Nov;
19(11):e3001445.
PMID: 34758021
Cochlear supporting cells (SCs) are glia-like cells critical for hearing function. In the neonatal cochlea, the greater epithelial ridge (GER) is a mitotically quiescent and transient organ, which has been...
10.
Sun H, Wang T, Atkinson P, Billings S, Dong W, Cheng A
Front Cell Dev Biol
. 2021 Aug;
9:690955.
PMID: 34395423
The G protein-coupled receptor (GPR) family critically regulates development and homeostasis of multiple organs. As a member of the GPR adhesion family, Gpr125 (Adgra3) modulates Wnt/PCP signaling and convergent extension...