Patrick H Maxwell
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Explore the profile of Patrick H Maxwell including associated specialties, affiliations and a list of published articles.
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167
Citations
8519
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Recent Articles
1.
Schubert T, Oosterlinck T, Stevens R, Maxwell P, van der Schaar M
EClinicalMedicine
. 2024 Dec;
79:102968.
PMID: 39720600
Rapid advancements in medical AI necessitate targeted educational initiatives for clinicians to ensure AI tools are safe and used effectively to improve patient outcomes. To support decision-making among stakeholders in...
2.
Maxwell P, Mahmood M, Villanueva M, Devine K, Avery N
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408922
Retrotransposons are mobile DNA elements that are more active with increasing age and exacerbate aging phenotypes in multiple species. We previously reported an unexpected extension of chronological lifespan in the...
3.
Meng B, Zhao N, Mlcochova P, Ferreira I, Ortmann B, Davis T, et al.
Cell Rep
. 2024 Jul;
43(7):114471.
PMID: 38996069
Low-oxygen conditions (hypoxia) have been associated primarily with cell-cycle arrest in dividing cells. Macrophages are typically quiescent in G0 but can proliferate in response to tissue signals. Here we show...
4.
Xu J, Guo P, Hao S, Shangguan S, Shi Q, Volpe G, et al.
Nat Genet
. 2024 Apr;
56(5):953-969.
PMID: 38627598
The mechanism by which mammalian liver cell responses are coordinated during tissue homeostasis and perturbation is poorly understood, representing a major obstacle in our understanding of many diseases. This knowledge...
5.
Cao J, Li W, Li J, Mazid M, Li C, Jiang Y, et al.
Cell
. 2023 Nov;
186(23):4996-5014.e24.
PMID: 37949056
A formal demonstration that mammalian pluripotent stem cells possess preimplantation embryonic cell-like (naive) pluripotency is the generation of chimeric animals through early embryo complementation with homologous cells. Whereas such naive...
6.
Wang J, Xie W, Li N, Li W, Zhang Z, Fan N, et al.
Cell Stem Cell
. 2023 Sep;
30(9):1235-1245.e6.
PMID: 37683604
Heterologous organ transplantation is an effective way of replacing organ function but is limited by severe organ shortage. Although generating human organs in other large mammals through embryo complementation would...
7.
Lesage P, Maxwell P
Proc Natl Acad Sci U S A
. 2023 Aug;
120(35):e2311419120.
PMID: 37590432
No abstract available.
8.
Zhang X, Lai G, Volpe G, Han L, Maxwell P, Liu L, et al.
Zool Res
. 2022 Jul;
43(4):691-694.
PMID: 35838039
No abstract available.
9.
Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, et al.
Cell
. 2022 May;
185(10):1777-1792.e21.
PMID: 35512705
Spatially resolved transcriptomic technologies are promising tools to study complex biological processes such as mammalian embryogenesis. However, the imbalance between resolution, gene capture, and field of view of current methodologies...
10.
Han L, Wei X, Liu C, Volpe G, Zhuang Z, Zou X, et al.
Nature
. 2022 Apr;
604(7907):723-731.
PMID: 35418686
Studying tissue composition and function in non-human primates (NHPs) is crucial to understand the nature of our own species. Here we present a large-scale cell transcriptomic atlas that encompasses over...