Patrick Groves
Overview
Explore the profile of Patrick Groves including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
212
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Recent Articles
1.
Komiazyk M, Palczewska M, Sitkiewicz I, Pikula S, Groves P
BMC Complement Altern Med
. 2019 Jun;
19(1):140.
PMID: 31221152
Background: Cholera is one of the most deadly diarrheal diseases that require new treatments. We investigated the neutralization of cholera toxin by five plant extracts obtained from the Rosaceae family...
2.
Jurczak P, Groves P, Szymanska A, Rodziewicz-Motowidlo S
FEBS Lett
. 2016 Nov;
590(23):4192-4201.
PMID: 27766618
Human cystatin C (hCC) is a small protein belonging to the cystatin family of papain-like cysteine proteinase inhibitors. We review the recent literature concerning structural aspects of hCC related to...
3.
Komiazyk M, Palczewska M, Pikula S, Groves P
Postepy Biochem
. 2016 Apr;
61(4):430-5.
PMID: 27048097
One of the main factors causing bacterial diarrhea are AB₅ enterotoxins. This group is divided into four families: pertussis toxin, cholera toxin, shiga toxin and subtilase cytotoxin. In this review...
4.
Cmoch A, Podszywalow-Bartnicka P, Palczewska M, Piwocka K, Groves P, Pikula S
PLoS One
. 2014 Oct;
9(10):e109938.
PMID: 25314307
Background: Osteosarcoma (OS) is a highly aggressive bone cancer affecting children and young adults. Growing evidence connects the invasive potential of OS cells with their ability to form invadopodia (structures...
5.
Komiazyk M, Palczewska M, Sitkiewicz I, Groves P
Pol J Microbiol
. 2014 Jul;
63(1):3-14.
PMID: 25033656
Plants contain a broad spectrum of small molecules with potential antimicrobial properties. Here, we review the antimicrobial activities of plant extracts against enterotoxic bacteria encoding AB5 toxins, including Vibrio cholerae,...
6.
Cmoch A, Groves P, Pikula S
Postepy Biochem
. 2014 Jul;
60(1):62-8.
PMID: 25033543
Cancer cells degrade the extracellular matrix (ECM) in the basement membrane and blood vessel walls to emigrate and invade from original to peripheral tissues. This invasion of cells through ECM...
7.
Groves P, Strzelecka-Kiliszek A, Sekrecka-Belniak A, Canales A, Jimenez-Barbero J, Bandorowicz-Pikula J, et al.
Org Biomol Chem
. 2013 Jul;
11(32):5332-8.
PMID: 23842795
Fluorescent analogues provide important tools for biochemical/biophysical research. However, the analogues contain chemical modifications much larger than those known to affect ligand-binding, such as the inversion of a carbon centre...
8.
Cmoch A, Groves P, Palczewska M, Pikula S
Postepy Biochem
. 2013 May;
58(4):429-36.
PMID: 23662436
Calcium ions are essential factors controlling the balance between cell survival, growth, differentiation and metabolism. Ca2+ acts as a global second messenger involved in the regulation of all aspects of...
9.
Mateus P, Delgado R, Groves P, Campos S, Baptista A, Brandao P, et al.
J Org Chem
. 2012 Jul;
77(16):6816-24.
PMID: 22834635
A new heteroditopic macrobicyclic compound (t(2)pN(5)O(3)) containing two separate polyoxa and polyaza compartments was synthesized in good yield through a [1 + 1] "tripod-tripod coupling" strategy. The X-ray crystal structure...
10.
Reinstein O, Neves M, Saad M, Boodram S, Lombardo S, Beckham S, et al.
Biochemistry
. 2011 Sep;
50(43):9368-76.
PMID: 21942676
The steroid binding mechanism of a DNA aptamer was studied using isothermal titration calorimetry (ITC), NMR spectroscopy, quasi-elastic light scattering (QELS), and small-angle X-ray spectroscopy (SAXS). Binding affinity determination of...