Patricia Sanchez-Vazquez
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Explore the profile of Patricia Sanchez-Vazquez including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
716
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Recent Articles
1.
Sanchez-Vazquez P, Dewey C, Kitten N, Ross W, Gourse R
Proc Natl Acad Sci U S A
. 2019 Apr;
116(17):8310-8319.
PMID: 30971496
The second messenger nucleotide ppGpp dramatically alters gene expression in bacteria to adjust cellular metabolism to nutrient availability. ppGpp binds to two sites on RNA polymerase (RNAP) in , but...
2.
Gourse R, Chen A, Gopalkrishnan S, Sanchez-Vazquez P, Myers A, Ross W
Annu Rev Microbiol
. 2018 Sep;
72:163-184.
PMID: 30200857
The stringent response to nutrient deprivation is a stress response found throughout the bacterial domain of life. Although first described in proteobacteria for matching ribosome synthesis to the cell's translation...
3.
Burgos H, OConnor K, Sanchez-Vazquez P, Gourse R
J Bacteriol
. 2017 Aug;
199(21).
PMID: 28784818
Bacterial ribosome biogenesis is tightly regulated to match nutritional conditions and to prevent formation of defective ribosomal particles. In , most ribosomal protein (r-protein) synthesis is coordinated with rRNA synthesis...
4.
Gaal T, Bratton B, Sanchez-Vazquez P, Sliwicki A, Sliwicki K, Vegel A, et al.
Genes Dev
. 2016 Nov;
30(20):2272-2285.
PMID: 27898392
The spatial organization of DNA within the bacterial nucleoid remains unclear. To investigate chromosome organization in Escherichia coli, we examined the relative positions of the ribosomal RNA (rRNA) operons in...
5.
Ross W, Sanchez-Vazquez P, Chen A, Lee J, Burgos H, Gourse R
Mol Cell
. 2016 May;
62(6):811-823.
PMID: 27237053
Throughout the bacterial domain, the alarmone ppGpp dramatically reprograms transcription following nutrient limitation. This "stringent response" is critical for survival and antibiotic tolerance and is a model for transcriptional regulation...
6.
Ross W, Vrentas C, Sanchez-Vazquez P, Gaal T, Gourse R
Mol Cell
. 2013 Apr;
50(3):420-9.
PMID: 23623682
The global regulatory nucleotide ppGpp ("magic spot") regulates transcription from a large subset of Escherichia coli promoters, illustrating how small molecules can control gene expression promoter-specifically by interacting with RNA...
7.
Hsu C, Muerdter C, Knickerbocker A, Walsh R, Zepeda-Rivera M, Depner K, et al.
Dev Dyn
. 2012 Aug;
241(10):1545-61.
PMID: 22911626
Background: We investigated the roles of p120 catenin, Cdc42, Rac1, and RhoA GTPases in regulating migration of presomitic mesoderm cells in zebrafish embryos. p120 catenin has dual roles: It binds...
8.
Lemke J, Sanchez-Vazquez P, Burgos H, Hedberg G, Ross W, Gourse R
Proc Natl Acad Sci U S A
. 2011 Mar;
108(14):5712-7.
PMID: 21402902
We show here that the promoters for many of the Escherichia coli ribosomal protein operons are regulated directly by two transcription factors, the small RNA polymerase-binding protein DksA and the...