Patricia R Oprysko
Overview
Explore the profile of Patricia R Oprysko including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
87
Followers
0
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Recent Articles
1.
Tuttle S, Maity A, Oprysko P, Kachur A, Ayene I, Biaglow J, et al.
J Biol Chem
. 2007 Aug;
282(51):36790-6.
PMID: 17666400
The oxidative pentose phosphate cycle (OPPC) is necessary to maintain cellular reducing capacity during periods of increased oxidative stress. Metabolic flux through the OPPC increases stoichiometrically in response to a...
2.
Pan Y, Oprysko P, Asham A, Koch C, Simon M
Oncogene
. 2004 Apr;
23(29):4975-83.
PMID: 15107830
Solid tumors frequently contain hypoxic subregions due to insufficient blood supply. In these domains, cells can undergo p53-dependent apoptosis. Therefore, hypoxia has been implicated as a physiological stimulus for p53...
3.
Koch C, Oprysko P, Shuman A, Jenkins W, Brandt G, Evans S
Cancer Res
. 2002 Jul;
62(13):3626-9.
PMID: 12097264
One method to make hypoxic, radioresistant cells more radiation sensitive has been to increase the oxygen carrying capacity of normal blood using liquid perfluorochemical emulsions combined with breathing high pO2...