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Patricia P Smith

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Articles 13
Citations 462
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Recent Articles
1.
Weber W, Labriola C, Kreklywich C, Ray K, Haese N, Andoh T, et al.
PLoS Negl Trop Dis . 2023 Nov; 17(11):e0011742. PMID: 37983245
Mayaro virus (MAYV) is a mosquito-transmitted alphavirus that causes debilitating and persistent arthritogenic disease. While MAYV was previously reported to infect non-human primates (NHP), characterization of MAYV pathogenesis is currently...
2.
Gatault P, Jones I, Meyer C, Kreklywich C, Alexander T, Smith P, et al.
Virology . 2021 Feb; 557:23-33. PMID: 33601113
Herpesviruses encode multiple glycoproteins required for different stages of viral attachment, fusion, and envelopment. The protein encoded by the human cytomegalovirus (HCMV) open reading frame UL116 forms a stable complex...
3.
Haese N, Burg J, Andoh T, Jones I, Kreklywich C, Smith P, et al.
Transpl Infect Dis . 2020 Nov; 23(2):e13514. PMID: 33205500
Cytomegalovirus (CMV) infection is linked to acceleration of solid organ transplant vascular sclerosis (TVS) and chronic rejection (CR). Donor latent CMV infection increases cardiac-resident macrophages and T cells leading to...
4.
Crawford L, Caposio P, Kreklywich C, Pham A, Hancock M, Jones T, et al.
mBio . 2019 Aug; 10(4). PMID: 31431555
Human cytomegalovirus (HCMV) infection of CD34 hematopoietic progenitor cells (CD34 HPCs) provides a critical reservoir of virus in stem cell transplant patients, and viral reactivation remains a significant cause of...
5.
Broeckel R, Fox J, Haese N, Kreklywich C, Sukulpovi-Petty S, Legasse A, et al.
PLoS Negl Trop Dis . 2017 Jun; 11(6):e0005637. PMID: 28628616
Chikungunya virus (CHIKV) is a mosquito-borne virus that causes a febrile syndrome in humans associated with acute and chronic debilitating joint and muscle pain. Currently no licensed vaccines or therapeutics...
6.
Hirsch A, Smith J, Haese N, Broeckel R, Parkins C, Kreklywich C, et al.
PLoS Pathog . 2017 Apr; 13(4):e1006317. PMID: 28380070
[This corrects the article DOI: 10.1371/journal.ppat.1006219.].
7.
Hirsch A, Smith J, Haese N, Broeckel R, Parkins C, Kreklywich C, et al.
PLoS Pathog . 2017 Mar; 13(3):e1006219. PMID: 28278237
Zika virus (ZIKV), an emerging flavivirus, has recently spread explosively through the Western hemisphere. In addition to symptoms including fever, rash, arthralgia, and conjunctivitis, ZIKV infection of pregnant women can...
8.
MacManiman J, Meuser A, Botto S, Smith P, Liu F, Jarvis M, et al.
mBio . 2014 Oct; 5(6):e02035. PMID: 25352622
Unlabelled: Persistent human cytomegalovirus (HCMV) infection has been linked to several diseases, including atherosclerosis, transplant vascular sclerosis (TVS), restenosis, and glioblastoma. We have previously shown that factors secreted from HCMV-infected...
9.
Pal P, Fox J, Hawman D, Huang Y, Messaoudi I, Kreklywich C, et al.
J Virol . 2014 May; 88(15):8213-26. PMID: 24829346
Unlabelled: Chikungunya virus (CHIKV) is a reemerging mosquito-transmitted alphavirus that causes epidemics of debilitating polyarthritis in humans. A prior study identified two anti-CHIKV monoclonal antibodies ([MAbs] CHK-152 and CHK-166) against...
10.
Kreklywich C, Smith P, Jones C, Cornea A, Orloff S, Streblow D
Methods Mol Biol . 2014 Mar; 1119:217-37. PMID: 24639226
Cytomegalovirus gene expression in highly permissive, cultured fibroblasts occurs in three kinetic classes known as immediate early, early, and late. Infection of these cells results in a predictable transcriptional program...