Patricia Maciel
Overview
Explore the profile of Patricia Maciel including associated specialties, affiliations and a list of published articles.
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Articles
109
Citations
1807
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Recent Articles
1.
Silva A, Duarte-Silva S, Martins P, Rodrigues B, Serrenho D, Vilasboas-Campos D, et al.
bioRxiv
. 2025 Feb;
PMID: 39896516
Spinocerebellar ataxia type 3 (SCA3) is a rare inherited neurodegenerative disease caused by the expansion of a polyglutamine repeat in the protease ataxin-3 (Atx3). Despite extensive knowledge of the downstream...
2.
Carvalho L, Pedroso de Lima F, Cerqueira M, Silva A, Pontes O, Oliveira-Pinto S, et al.
RSC Med Chem
. 2024 Apr;
15(4):1362-1380.
PMID: 38665823
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, and the limited therapeutic options show poor efficacy in patients, associated to severe side effects and development of...
3.
Chatterjee N, Gonzalez-Durruthy M, Costa M, Ribeiro A, Vilas-Boas V, Vilasboas-Campos D, et al.
Environ Int
. 2024 Apr;
186:108597.
PMID: 38579453
The growing body of evidence links exposure to particulate matter pollutants with an increased risk of neurodegenerative diseases. In the present study, we investigated whether diesel exhaust particles can induce...
4.
Pohl F, Lindsay-McGee V, Kong Thoo Lin P, Maciel P, Teixeira-Castro A
MicroPubl Biol
. 2024 Feb;
2024.
PMID: 38404918
Inhibition of acetylcholinesterase (AChE) is a common used treatment option for Alzheimer's disease. However, there has been limited research on the potential use of AChE inhibitors for the treatment of...
5.
Chatterjee A, Saha S, Chakraborty A, Silva-Fernandes A, Mandal S, Neves-Carvalho A, et al.
PLoS Genet
. 2024 Jan;
20(1):e1011124.
PMID: 38236804
[This corrects the article DOI: 10.1371/journal.pgen.1004749.].
6.
Duarte-Silva S, Da Silva J, Monteiro-Fernandes D, Costa M, Neves-Carvalho A, Raposo M, et al.
J Clin Invest
. 2024 Jan;
134(5).
PMID: 38227368
Spinocerebellar ataxia type 3 (SCA3) is an adult-onset neurodegenerative disease caused by a polyglutamine expansion in the ataxin-3 (ATXN3) gene. No effective treatment is available for this disorder, other than...
7.
Almeida F, Ferreira I, Naia L, Marinho D, Vilaca-Ferreira A, Costa M, et al.
Cells
. 2023 Oct;
12(19).
PMID: 37830611
Mitochondrial dysfunction has been described in many neurodegenerative disorders; however, there is less information regarding mitochondrial deficits in Machado-Joseph disease (MJD), a polyglutamine (polyQ) disorder caused by CAG repeat expansion...
8.
Figueiredo F, Sarkany Z, Silva A, Vilasboas-Campos D, Maciel P, Teixeira-Castro A, et al.
Biomed Pharmacother
. 2023 Aug;
165:115258.
PMID: 37549460
The accumulation of mutant ataxin-3 (Atx3) in neuronal nuclear inclusions is a pathological hallmark of Machado-Joseph disease (MJD), also known as Spinocerebellar Ataxia Type 3. Decreasing the protein aggregation burden...
9.
Cunha-Garcia D, Monteiro-Fernandes D, Correia J, Neves-Carvalho A, Vilaca-Ferreira A, Guerra-Gomes S, et al.
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37445783
Spinocerebellar ataxia type 3 (SCA3) is a rare neurodegenerative disease caused by an abnormal polyglutamine expansion within the ataxin-3 protein (ATXN3). This leads to neurodegeneration of specific brain and spinal...
10.
Teixeira-Castro A, Sousa J, Vieira C, Pereira-Sousa J, Vilasboas-Campos D, Marques F, et al.
Biomedicines
. 2023 Jun;
11(6).
PMID: 37371826
Aim: Experimental models are a powerful aid in visualizing molecular phenomena. This work reports how the worm () can be effectively explored for students to learn how molecular cues dramatically...