Patricia Freitag
Overview
Explore the profile of Patricia Freitag including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
422
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0
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Recent Articles
1.
Aix E, Gallinat A, Yago-Diez C, Lucas J, Gomez M, Benguria A, et al.
Circulation
. 2023 May;
147(21):1634-1636.
PMID: 37216436
No abstract available.
2.
Carrillo Garcia C, Becker C, Forster M, Lohmann S, Freitag P, Laufer S, et al.
J Med Chem
. 2021 Nov;
65(2):1505-1524.
PMID: 34818008
Restoring lost heart muscle is an attractive goal for cardiovascular regenerative medicine. One appealing strategy is the therapeutic stimulation of cardiomyocyte proliferation, which remains challenging due to available assay technologies...
3.
Roell W, Klein A, Breitbach M, Becker T, Parikh A, Lee J, et al.
Sci Rep
. 2018 May;
8(1):7145.
PMID: 29739982
Ventricular tachycardia (VT) is the most common and potentially lethal complication following myocardial infarction (MI). Biological correction of the conduction inhomogeneity that underlies re-entry could be a major advance in...
4.
Frede S, Stockmann C, Winning S, Freitag P, Fandrey J
J Immunol
. 2017 Jul;
199(3):1206.
PMID: 28739595
No abstract available.
5.
Frede S, Freitag P, Geuting L, Konietzny R, Fandrey J
Blood
. 2011 Mar;
117(18):4905-14.
PMID: 21406725
Erythropoietin (EPO), the key hormone in red blood cell renewal, is mainly produced in the adult kidney. Anemia and hypoxia substantially enhance EPO expression to increase erythropoiesis. Investigations of the...
6.
Frede S, Stockmann C, Winning S, Freitag P, Fandrey J
J Immunol
. 2009 May;
182(10):6470-6.
PMID: 19414801
The oxygen-sensitive transcription factor hypoxia-inducible factor 1 (HIF-1) is known as the key regulator of hypoxia-induced gene expression. In addition to hypoxia, endotoxins such as bacterial LPS as well as...
7.
Bramey T, Freitag P, Fandrey J, Rauen U, Pamp K, Erhard J, et al.
BMC Gastroenterol
. 2009 Apr;
9:26.
PMID: 19383129
Background: Recombinant human erythropoietin alpha (rHu-EPO) has been reported to protect the liver of rats and mice from ischemia-reperfusion injury. However, direct protective effects of rHu-EPO on hepatocytes and the...
8.
Wasserfuhr D, Cetin S, Yang J, Freitag P, Frede S, Jakob H, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2008 May;
378(1):27-32.
PMID: 18488199
We have previously shown that 2 weeks of hypoxia protect the right ventricle of the rat heart from subsequent ischemia and reperfusion (I/R). In the present study, we examined the...
9.
Frede S, Stockmann C, Freitag P, Fandrey J
Biochem J
. 2006 Mar;
396(3):517-27.
PMID: 16533170
Inflammatory mediators activate the transcriptional complex HIF-1 (hypoxia-inducible factor-1), the key regulator of hypoxia-induced gene expression. Here we report that bacterial LPS (lipopolysaccharide) induces HIF-1alpha mRNA expression and HIF-1alpha protein...
10.
Burmester H, Wolber E, Freitag P, Fandrey J, Jelkmann W
J Interferon Cytokine Res
. 2005 Jul;
25(7):407-13.
PMID: 16022585
Clinical and laboratory studies indicate that thrombopoietin (TPO) gene expression increases during inflammation. To clarify the role of interleukin 6 (IL-6) in this process, blood cell counts, plasma TPO concentrations,...