Patricia C Galipeau
Overview
Explore the profile of Patricia C Galipeau including associated specialties, affiliations and a list of published articles.
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25
Citations
1422
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Recent Articles
1.
Luebeck J, Ng A, Galipeau P, Li X, Sanchez C, Katz-Summercorn A, et al.
Nature
. 2023 Apr;
616(7958):798-805.
PMID: 37046089
Oncogene amplification on extrachromosomal DNA (ecDNA) drives the evolution of tumours and their resistance to treatment, and is associated with poor outcomes for patients with cancer. At present, it is...
2.
Paulson T, Galipeau P, Oman K, Sanchez C, Kuhner M, Smith L, et al.
Nat Commun
. 2022 Apr;
13(1):2300.
PMID: 35484108
While the genomes of normal tissues undergo dynamic changes over time, little is understood about the temporal-spatial dynamics of genomes in premalignant tissues that progress to cancer compared to those...
3.
Smith L, Yamato J, Galipeau P, Paulson T, Li X, Sanchez C, et al.
Evol Appl
. 2021 Mar;
14(2):399-415.
PMID: 33664784
Barrett's Esophagus is a neoplastic condition which progresses to esophageal adenocarcinoma in 5% of cases. Key events affecting the outcome likely occur before diagnosis of Barrett's and cannot be directly...
4.
Hadi K, Yao X, Behr J, Deshpande A, Xanthopoulakis C, Tian H, et al.
Cell
. 2020 Oct;
183(1):197-210.e32.
PMID: 33007263
Cancer genomes often harbor hundreds of somatic DNA rearrangement junctions, many of which cannot be easily classified into simple (e.g., deletion) or complex (e.g., chromothripsis) structural variant classes. Applying a...
5.
Galipeau P, Oman K, Paulson T, Sanchez C, Zhang Q, Marty J, et al.
Genome Med
. 2019 Mar;
11(1):14.
PMID: 30867038
It was highlighted that in the original article [1] the Availability of data and materials section was incorrect.
6.
Galipeau P, Oman K, Paulson T, Sanchez C, Zhang Q, Marty J, et al.
Genome Med
. 2018 Mar;
10(1):17.
PMID: 29486792
Background: Use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been shown to protect against tetraploidy, aneuploidy, and chromosomal alterations in the metaplastic condition Barrett's esophagus (BE) and to...
7.
Li X, Paulson T, Galipeau P, Sanchez C, Liu K, Kuhner M, et al.
Cancer Prev Res (Phila)
. 2015 Jul;
8(9):845-56.
PMID: 26130253
Cancers detected at a late stage are often refractory to treatments and ultimately lethal. Early detection can significantly increase survival probability, but attempts to reduce mortality by early detection have...
8.
Buas M, Levine D, Makar K, Utsugi H, Onstad L, Li X, et al.
Carcinogenesis
. 2014 Oct;
35(12):2740-7.
PMID: 25280564
Incidence of esophageal adenocarcinoma (EA) in Western countries has increased markedly in recent decades. Although several risk factors have been identified for EA and its precursor, Barrett's esophagus (BE), including...
9.
Li X, Galipeau P, Paulson T, Sanchez C, Arnaudo J, Liu K, et al.
Cancer Prev Res (Phila)
. 2013 Nov;
7(1):114-27.
PMID: 24253313
All cancers are believed to arise by dynamic, stochastic somatic genomic evolution with genome instability, generation of diversity, and selection of genomic alterations that underlie multistage progression to cancer. Advanced...
10.
Kostadinov R, Kuhner M, Li X, Sanchez C, Galipeau P, Paulson T, et al.
PLoS Genet
. 2013 Jun;
9(6):e1003553.
PMID: 23785299
Cancer is considered an outcome of decades-long clonal evolution fueled by acquisition of somatic genomic abnormalities (SGAs). Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce cancer risk, including risk...