Patience Browne
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Explore the profile of Patience Browne including associated specialties, affiliations and a list of published articles.
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24
Citations
721
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Recent Articles
1.
Hopf N, Bessems J, Santonen T, Viegas S, Casteleyn L, Poddalgoda D, et al.
Toxicol Lett
. 2024 Dec;
403():132-143.
PMID: 39681241
Derivation of occupational biomonitoring levels (OBLs) is needed to effectively utilize biomonitoring for assessing exposures to chemical substances, and consequently, implement risk reduction measures to reduce health risks among workers....
2.
Hopf N, Rousselle C, Poddalgoda D, Lamkarkach F, Bessems J, Schmid K, et al.
Environ Int
. 2024 Sep;
191:108990.
PMID: 39244955
Biomonitoring has been widely used in assessing exposures in both occupational and public health complementing chemical risk assessments because it measures the concentrations of chemical substances in human body fluids...
3.
Browne P, Paul Friedman K, Boekelheide K, Thomas R
Regul Toxicol Pharmacol
. 2024 Feb;
148:105579.
PMID: 38309424
Chemical safety assessment begins with defining the lowest level of chemical that alters one or more measured endpoints. This critical effect level, along with factors to account for uncertainty, is...
4.
Carnesecchi E, Langezaal I, Browne P, Batista-Leite S, Campia I, Coecke S, et al.
Regul Toxicol Pharmacol
. 2023 Jun;
142:105426.
PMID: 37277057
In the European Union, the Chemicals Strategy for Sustainability (CSS) highlights the need to enhance the identification and assessment of substances of concern while reducing animal testing, thus fostering the...
5.
Krewski D, Saunders-Hastings P, Baan R, Barton-Maclaren T, Browne P, Chiu W, et al.
ALTEX
. 2022 Sep;
39(4):667-693.
PMID: 36098377
Assessment of potential human health risks associated with environmental and other agents requires careful evaluation of all available and relevant evidence for the agent of interest, including both data-rich and...
6.
Casati S, Asturiol D, Browne P, Kleinstreuer N, Regimbald-Krnel M, Therriault P
Front Toxicol
. 2022 Aug;
4:943152.
PMID: 36032790
In the absence of stand-alone one-to-one replacements for existing animal tests, efforts were made to integrate data from , and methods to ensure sufficient mechanistic coverage of the skin sensitisation...
7.
van der Zalm A, Barroso J, Browne P, Casey W, Gordon J, Henry T, et al.
Arch Toxicol
. 2022 Aug;
96(11):2865-2879.
PMID: 35987941
Robust and efficient processes are needed to establish scientific confidence in new approach methodologies (NAMs) if they are to be considered for regulatory applications. NAMs need to be fit for...
8.
LaLone C, Basu N, Browne P, Edwards S, Embry M, Sewell F, et al.
Environ Toxicol Chem
. 2021 Sep;
40(12):3226-3233.
PMID: 34551147
No abstract available.
9.
Park Y, Jung D, Milcamps A, Takeyoshi M, Jacobs M, Houck K, et al.
Food Chem Toxicol
. 2021 Apr;
152:112206.
PMID: 33887398
We describe the characterisation and validation of an androgen receptor (AR) transactivation assay for detection of AR agonists and antagonists using a stably transfected human prostate cancer cell line. This...
10.
De Vries R, Angrish M, Browne P, Brozek J, Rooney A, Wikoff D, et al.
ALTEX
. 2021 Apr;
38(2):336-347.
PMID: 33837437
The workshop “Application of evidence-based methods to construct mechanistic frameworks for the development and use of non-animal toxicity tests” was organized by the Evidence-based Toxicology Collaboration and hosted by the...