Pasi Kallio
Overview
Explore the profile of Pasi Kallio including associated specialties, affiliations and a list of published articles.
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Articles
40
Citations
484
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Recent Articles
1.
Mahdavi R, Hashemi-Najafabadi S, Ghiass M, Valaskivi S, Valimaki H, Kreutzer J, et al.
Biomed Microdevices
. 2025 Feb;
27(1):8.
PMID: 39953294
Liver zonation is a fundamental characteristic of hepatocyte spatial heterogeneity, which is challenging to recapitulate in traditional cell cultures. This study presents a novel microfluidic device designed to induce zonation...
2.
Yrjanainen A, Mesia E, Lampela E, Kreutzer J, Vihinen J, Tornberg K, et al.
Sci Rep
. 2024 Oct;
14(1):22916.
PMID: 39358415
Developing microphysiological cell culture platforms with a three-dimensional (3D) microenvironment has been a significant advancement from traditional monolayer cultures. Still, most of the current microphysiological platforms are limited in closed...
3.
Kapucu F, Tujula I, Kulta O, Sukki L, Ryynanen T, Gram H, et al.
NPJ Parkinsons Dis
. 2024 Jul;
10(1):138.
PMID: 39069518
Previous studies have shown that aggregated alpha-synuclein (α-s) protein, a key pathological marker of Parkinson's disease (PD), can propagate between cells, thus participating in disease progression. This prion-like propagation has...
4.
Kauppila M, Moro A, Valle-Delgado J, Ihalainen T, Sukki L, Puistola P, et al.
Adv Healthc Mater
. 2023 Jul;
12(29):e2301396.
PMID: 37449943
A functional limbal epithelial stem cells (LSC) niche is a vital element in the regular renewal of the corneal epithelium by LSCs and maintenance of good vision. However, little is...
5.
Santiago J, Kreutzer J, Bossink E, Kallio P, le Feber J
Front Neurosci
. 2023 Apr;
17:1110083.
PMID: 37056304
Introduction: In the core of a brain infarct, perfusion is severely impeded, and neuronal death occurs within minutes. In the penumbra, an area near the core with more remaining perfusion,...
6.
Hakli M, Kreutzer J, Maki A, Valimaki H, Cherian R, Kallio P, et al.
Stem Cells Int
. 2022 Dec;
2022:9438281.
PMID: 36579142
Ischemic heart disease is the most common cardiovascular disease and a major burden for healthcare worldwide. However, its pathophysiology is still not fully understood, and human-based models for disease mechanisms...
7.
Tornberg K, Valimaki H, Valaskivi S, Maki A, Jokinen M, Kreutzer J, et al.
Biomed Microdevices
. 2022 Oct;
24(4):34.
PMID: 36269438
Hypoxia is a condition where tissue oxygen levels fall below normal levels. In locally induced hypoxia due to blood vessel blockage, oxygen delivery becomes compromised. The site where blood flow...
8.
Peussa H, Kreutzer J, Mantyla E, Maki A, Nymark S, Kallio P, et al.
PLoS One
. 2022 Jun;
17(6):e0268570.
PMID: 35657824
It is well established that mechanical cues, e.g., tensile- compressive- or shear forces, are important co-regulators of cell and tissue physiology. To understand the mechanistic effects these cues have on...
9.
Hakli M, Jantti S, Joki T, Sukki L, Tornberg K, Aalto-Setala K, et al.
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328569
The cardiac autonomic nervous system (cANS) regulates cardiac function by innervating cardiac tissue with axons, and cardiomyocytes (CMs) and neurons undergo comaturation during the heart innervation in embryogenesis. As cANS...
10.
Gaballah M, Penttinen K, Kreutzer J, Maki A, Kallio P, Aalto-Setala K
Cells
. 2022 Mar;
11(6).
PMID: 35326497
Ischemic heart disease (IHD) is one of the leading causes of mortality worldwide. Preserving functionality and preventing arrhythmias of the heart are key principles in the management of patients with...