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Pascale Bomont

Explore the profile of Pascale Bomont including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 2180
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Recent Articles
1.
Veena M, Gahng J, Alani M, Ko A, Basak S, Liu I, et al.
Cancer Res Commun . 2024 Feb; 4(3):706-722. PMID: 38421310
Significance: Our results suggest that GAN gene exon 8 SNP T allele expression correlates with higher gigaxonin expression and suppression of aggressive cancer cell growth. There is downregulation of Snail...
2.
van Asperen J, Kotaich F, Caillol D, Bomont P
Curr Opin Cell Biol . 2024 Feb; 87:102326. PMID: 38401181
Neurofilaments (NFs) are abundant cytoskeletal proteins that emerge as a critical hub for cell signalling within neurons. As we start to uncover essential roles of NFs in regulating microtubule and...
3.
Lienard C, Pintart A, Bomont P
Cells . 2024 Jan; 13(1). PMID: 38201307
Autophagy is a major degradative pathway that plays a key role in sustaining cell homeostasis, integrity, and physiological functions. Macroautophagy, which ensures the clearance of cytoplasmic components engulfed in a...
4.
Kotaich F, Caillol D, Bomont P
Front Cell Dev Biol . 2024 Jan; 11:1275155. PMID: 38164457
Neurofilaments (NFs) are the most abundant component of mature neurons, that interconnect with actin and microtubules to form the cytoskeleton. Specifically expressed in the nervous system, NFs present the particularity...
5.
Lescouzeres L, Hassen-Khodja C, Baudot A, Bordignon B, Bomont P
EMBO Mol Med . 2023 May; 15(7):e16267. PMID: 37144692
Giant axonal neuropathy (GAN) is a fatal neurodegenerative disorder for which there is currently no treatment. Affecting the nervous system, GAN starts in infancy with motor deficits that rapidly evolve...
6.
Lescouzeres L, Bordignon B, Bomont P
Front Mol Neurosci . 2022 Oct; 15:956582. PMID: 36204134
The zebrafish () is a vertebrate species offering multitude of advantages for the study of conserved biological systems in human and has considerably enriched our knowledge in developmental biology and...
7.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy . 2021 Feb; 17(1):1-382. PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
8.
Bomont P
Curr Opin Cell Biol . 2021 Jan; 68:181-191. PMID: 33454158
In the last two years, neurofilaments (NFs) have become one of the most blazing topics in clinical neuroscience. NFs are major cytoskeletal constituents of neurons, can be detected in body...
9.
Lescouzeres L, Bomont P
Front Physiol . 2020 Nov; 11:1022. PMID: 33192535
Ubiquitination is a dynamic post-translational modification that regulates the fate of proteins and therefore modulates a myriad of cellular functions. At the last step of this sophisticated enzymatic cascade, E3...
10.
Gafson A, Barthelemy N, Bomont P, Carare R, Durham H, Julien J, et al.
Brain . 2020 May; 143(7):1975-1998. PMID: 32408345
Interest in neurofilaments has risen sharply in recent years with recognition of their potential as biomarkers of brain injury or neurodegeneration in CSF and blood. This is in the context...