Pascale Bertrand
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Explore the profile of Pascale Bertrand including associated specialties, affiliations and a list of published articles.
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34
Citations
1497
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Recent Articles
11.
Zhang S, Pondarre C, Pennarun G, Labussiere-Wallet H, Vera G, France B, et al.
J Exp Med
. 2016 May;
213(6):1011-28.
PMID: 27185855
Inherited bone marrow failure syndromes are human conditions in which one or several cell lineages of the hemopoietic system are affected. They are present at birth or may develop progressively....
12.
Taty-Taty G, Chailleux C, Quaranta M, So A, Guirouilh-Barbat J, Lopez B, et al.
Nucleic Acids Res
. 2015 Nov;
44(4):1657-68.
PMID: 26578561
Repair of DNA double-strand breaks occurs in a chromatin context that needs to be modified and remodeled to allow suitable access to the different DNA repair machineries. Of particular importance...
13.
Millet R, Jolinon N, Nguyen X, Berger G, Cimarelli A, Greco A, et al.
J Virol
. 2015 Apr;
89(13):6824-34.
PMID: 25903339
Unlabelled: Adeno-associated virus (AAV) is a helper-dependent parvovirus that requires coinfection with adenovirus (AdV) or herpes simplex virus 1 (HSV-1) to replicate. In the absence of the helper virus, AAV...
14.
Guirouilh-Barbat J, Lambert S, Bertrand P, Lopez B
Front Genet
. 2014 Jun;
5:175.
PMID: 24966870
Homologous recombination (HR) is an evolutionarily conserved process that plays a pivotal role in the equilibrium between genetic stability and diversity. HR is commonly considered to be error-free, but several...
15.
Betermier M, Bertrand P, Lopez B
PLoS Genet
. 2014 Jan;
10(1):e1004086.
PMID: 24453986
DNA double-strand breaks (DSBs) are harmful lesions leading to genomic instability or diversity. Non-homologous end-joining (NHEJ) is a prominent DSB repair pathway, which has long been considered to be error-prone....
16.
Grabarz A, Guirouilh-Barbat J, Barascu A, Pennarun G, Genet D, Rass E, et al.
Cell Rep
. 2013 Oct;
5(1):21-8.
PMID: 24095737
The choice of the appropriate double-strand break (DSB) repair pathway is essential for the maintenance of genomic stability. Here, we show that the Bloom syndrome gene product, BLM, counteracts CtIP/MRE11-dependent...
17.
Barascu A, Le Chalony C, Pennarun G, Genet D, Zaarour N, Bertrand P
Nucleus
. 2012 Aug;
3(5):411-7.
PMID: 22895091
Progeroid phenotypes are mainly encountered in 2 types of syndromes: in laminopathies, which are characterized by nuclear shape abnormalities due to lamin A alteration, and in DNA damage response defect...
18.
Boubakour-Azzouz I, Bertrand P, Claes A, Lopez B, Rougeon F
Nucleic Acids Res
. 2012 Jun;
40(17):8381-91.
PMID: 22740656
Terminal deoxynucleotidyl transferase (TdT) is a DNA polymerase that increases the repertoire of antigen receptors by adding non-templated nucleotides (N-addition) to V(D)J recombination junctions. Despite extensive in vitro studies on...
19.
Chevalier F, Depagne J, Hem S, Chevillard S, Bensimon J, Bertrand P, et al.
Proteomics
. 2012 May;
12(11):1756-66.
PMID: 22623065
Secreted proteins play a key role in cell signaling and communication. We recently showed that ionizing radiations induced a delayed cell death of breast cancer cells, mediated by the death...
20.
Barascu A, Le Chalony C, Pennarun G, Genet D, Imam N, Lopez B, et al.
EMBO J
. 2012 Jan;
31(5):1080-94.
PMID: 22246186
We report crosstalk between three senescence-inducing conditions, DNA damage response (DDR) defects, oxidative stress (OS) and nuclear shape alterations. The recessive autosomal genetic disorder Ataxia telangiectasia (A-T) is associated with...