Pascale Bertrand
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Explore the profile of Pascale Bertrand including associated specialties, affiliations and a list of published articles.
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34
Citations
1497
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Recent Articles
1.
Picotto J, Cipressa F, Busso D, Cenci G, Bertrand P, Pennarun G
bioRxiv
. 2024 Dec;
PMID: 39651205
Separase plays a central role in chromosome separation during mitosis and in centrosome cycle. Tight control of separase activity is required to prevent unscheduled resolution of sister chromatid cohesion and...
2.
Leriche M, Bonnet C, Jana J, Chhetri G, Mennour S, Martineau S, et al.
Cell Rep
. 2023 Nov;
42(11):113412.
PMID: 37963016
RNA-binding proteins (RBPs) are found at replication forks, but their direct interaction with DNA-embedded RNA species remains unexplored. Here, we report that p53-binding protein 1 (53BP1), involved in the DNA...
3.
Pennarun G, Picotto J, Bertrand P
Genes (Basel)
. 2023 Apr;
14(4).
PMID: 37107534
The nuclear envelope (NE) in eukaryotic cells is essential to provide a protective compartment for the genome. Beside its role in connecting the nucleus with the cytoplasm, the NE has...
4.
Rass E, Willaume S, Bertrand P
Genes (Basel)
. 2022 Dec;
13(12).
PMID: 36553657
Double-strand breaks (DSBs) are toxic lesions that can be generated by exposure to genotoxic agents or during physiological processes, such as during V(D)J recombination. The repair of these DSBs is...
5.
Schellenbauer A, Guilly M, Grall R, Le Bars R, Paget V, Kortulewski T, et al.
Nucleic Acids Res
. 2021 Oct;
49(20):11728-11745.
PMID: 34718776
Canonical non-homologous end-joining (cNHEJ) is the prominent mammalian DNA double-strand breaks (DSBs) repair pathway operative throughout the cell cycle. Phosphorylation of Ku70 at ser27-ser33 (pKu70) is induced by DNA DSBs...
6.
Pennarun G, Picotto J, Etourneaud L, Redavid A, Certain A, Gauthier L, et al.
Nucleic Acids Res
. 2021 Sep;
49(17):9886-9905.
PMID: 34469544
Telomere maintenance is essential to preserve genomic stability and involves telomere-specific proteins, DNA replication and repair proteins. Lamins are key components of the nuclear envelope and play numerous roles, including...
7.
Etourneaud L, Moussa A, Rass E, Genet D, Willaume S, Chabance-Okumura C, et al.
Sci Adv
. 2021 Aug;
7(35).
PMID: 34452908
Double-strand breaks (DSBs) are harmful lesions and a major cause of genome instability. Studies have suggested a link between the nuclear envelope and the DNA damage response. Here, we show...
8.
Willaume S, Rass E, Fontanilla-Ramirez P, Moussa A, Wanschoor P, Bertrand P
Genes (Basel)
. 2021 Apr;
12(4).
PMID: 33918867
Double-stranded breaks (DSB), the most toxic DNA lesions, are either a consequence of cellular metabolism, programmed as in during V(D)J recombination, or induced by anti-tumoral therapies or accidental genotoxic exposure....
9.
Fontanilla P, Willaume S, Theze B, Moussa A, Pennarun G, Bertrand P
Med Sci (Paris)
. 2020 Dec;
36(12):1118-1128.
PMID: 33296628
The accumulation of senescent cells accompanies organismal aging. Senescent cells produce an inflammatory microenvironment that is conducive to the development of many age-related diseases. Here we describe the different situations...
10.
Martins I, Raza S, Voisin L, Dakhli H, Allouch A, Law F, et al.
Cell Death Dis
. 2018 Jun;
9(7):716.
PMID: 29915308
Even though cell death modalities elicited by anticancer chemotherapy and radiotherapy have been extensively studied, the ability of anticancer treatments to induce non-cell-autonomous death has never been investigated. By means...