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Pascale Beffy

Explore the profile of Pascale Beffy including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 282
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Recent Articles
1.
Ferrero E, Masini M, Carli M, Moscato S, Beffy P, Vaglini F, et al.
Mol Cell Endocrinol . 2024 Jun; 592:112294. PMID: 38838763
The aim of the present research was to explore the mechanisms underlying the role of dopamine in the regulation of insulin secretion in beta cells. The effect of dopamine on...
2.
Novelli M, Beffy P, Masini M, Vantaggiato C, Martino L, Marselli L, et al.
Chemosphere . 2020 Dec; 265:129103. PMID: 33288281
An association between exposure to environmental pollutants and diabetes risk has been repeatedly shown by epidemiological studies. However, the biological basis of this association still need to be clarified. In...
3.
Novelli M, Masiello P, Beffy P, Menegazzi M
Int J Mol Sci . 2020 Nov; 21(21). PMID: 33143088
Diabetes mellitus is a very common chronic disease with progressively increasing prevalence. Besides the well-known autoimmune and inflammatory pathogenesis of type 1 diabetes, in many people, metabolic changes and inappropriate...
4.
Masiello P, Novelli M, Beffy P, Menegazzi M
Phytother Res . 2020 Jun; 34(7):1471-1473. PMID: 32501634
No abstract available.
5.
Rizzo M, Beffy P, Del Carratore R, Falleni A, Pretini V, DAurizio R, et al.
Cell Death Dis . 2018 Oct; 9(11):1071. PMID: 30341284
Congenital myotonic dystrophy type 1 (CDM1) is characterized by severe symptoms that affect patients from birth, with 40% mortality in the neonatal period and impaired skeletal muscle development. In this...
6.
Novelli M, Beffy P, Gregorelli A, Porozov S, Mascia F, Vantaggiato C, et al.
J Pharm Pharmacol . 2017 Oct; 71(1):93-103. PMID: 28990659
Objectives: St John's wort extract (SJW) and its component hyperforin (HPF) were shown to potently inhibit cytokine-induced STAT-1 and NF-κB activation in pancreatic β cells and protect them against injury....
7.
Novelli M, Menegazzi M, Beffy P, Porozov S, Gregorelli A, Giacopelli D, et al.
Int J Biochem Cell Biol . 2016 Oct; 81(Pt A):92-104. PMID: 27780755
The extract of the herbaceous plant St. John's wort (SJW) and its phloroglucinol component hyperforin (HPF) were previously shown to inhibit cytokine-induced STAT-1 and NF-κB activation and prevent damage in...
8.
Vecoli C, Novelli M, Pippa A, Giacopelli D, Beffy P, Masiello P, et al.
PLoS One . 2014 Aug; 9(8):e104156. PMID: 25093405
Abnormalities in eNOS gene, possibly interacting with high fat diet (HFD), affect peripheral vascular function and glucose metabolism. The relative role of eNOS gene, HFD and metabolic derangement on coronary...
9.
Masullo M, Menegazzi M, Di Micco S, Beffy P, Bifulco G, Dal Bosco M, et al.
J Nat Prod . 2014 Jan; 77(3):543-9. PMID: 24417609
Garcinol (1), a polyisoprenylated benzophenone occurring in Garcinia species, has been reported to exert anti-inflammatory activity in LPS-stimulated macrophages, through inhibition of NF-κB and/or JAK/STAT-1 activation. In order to provide...
10.
La Marca M, Beffy P, Pugliese A, Longo V
PLoS One . 2014 Jan; 8(12):e83538. PMID: 24391783
Nad(p)h: quinone oxidoreductase and heme oxygenase-1 were induced, although to different degrees, at the transcriptional, protein and/or activity levels by the treatment. As for the Nrf2 transcription factor, a partial...