Pascal Lapebie
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Explore the profile of Pascal Lapebie including associated specialties, affiliations and a list of published articles.
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22
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1181
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Recent Articles
1.
Meneau F, Lapebie P, Daldello E, Le T, Chevalier S, Assaf S, et al.
Development
. 2024 Nov;
151(23).
PMID: 39576213
cAMP-PKA signaling initiates the crucial process of oocyte meiotic maturation in many animals, but inhibits it in vertebrates. To address this 'cAMP paradox', we exchanged the key PKA substrate ARPP19...
2.
Valach M, Moreira S, Petitjean C, Benz C, Butenko A, Flegontova O, et al.
BMC Biol
. 2023 May;
21(1):99.
PMID: 37143068
Background: Diplonemid flagellates are among the most abundant and species-rich of known marine microeukaryotes, colonizing all habitats, depths, and geographic regions of the world ocean. However, little is known about...
3.
Ottaviani A, Eid R, Zoccola D, Pousse M, Dubal J, Barajas E, et al.
Sci Rep
. 2020 Nov;
10(1):19937.
PMID: 33203910
Aging is a multifactorial process that results in progressive loss of regenerative capacity and tissue function while simultaneously favoring the development of a large array of age-related diseases. Evidence suggests...
4.
A G protein-coupled receptor mediates neuropeptide-induced oocyte maturation in the jellyfish Clytia
Quiroga Artigas G, Lapebie P, Leclere L, Bauknecht P, Uveira J, Chevalier S, et al.
PLoS Biol
. 2020 Mar;
18(3):e3000614.
PMID: 32126082
The reproductive hormones that trigger oocyte meiotic maturation and release from the ovary vary greatly between animal species. Identification of receptors for these maturation-inducing hormones (MIHs) and understanding how they...
5.
Lapebie P, Lombard V, Drula E, Terrapon N, Henrissat B
Nat Commun
. 2019 May;
10(1):2043.
PMID: 31053724
Unlike proteins, glycan chains are not directly encoded by DNA, but by the specificity of the enzymes that assemble them. Theoretical calculations have proposed an astronomical number of possible isomers...
6.
Leclere L, Horin C, Chevalier S, Lapebie P, Dru P, Peron S, et al.
Nat Ecol Evol
. 2019 Mar;
3(5):801-810.
PMID: 30858591
Jellyfish (medusae) are a distinctive life-cycle stage of medusozoan cnidarians. They are major marine predators, with integrated neurosensory, muscular and organ systems. The genetic foundations of this complex form are...
7.
Seshadri R, Leahy S, Attwood G, Teh K, Lambie S, Cookson A, et al.
Nat Biotechnol
. 2018 Mar;
36(4):359-367.
PMID: 29553575
Productivity of ruminant livestock depends on the rumen microbiota, which ferment indigestible plant polysaccharides into nutrients used for growth. Understanding the functions carried out by the rumen microbiota is important...
8.
Takeda N, Kon Y, Quiroga Artigas G, Lapebie P, Barreau C, Koizumi O, et al.
Development
. 2018 Jan;
145(2).
PMID: 29358214
Oocyte meiotic maturation is crucial for sexually reproducing animals, and its core cytoplasmic regulators are highly conserved between species. By contrast, the few known maturation-inducing hormones (MIHs) that act on...
9.
Wong M, Wang W, Couturier M, Razeq F, Lombard V, Lapebie P, et al.
Front Microbiol
. 2018 Jan;
8:2504.
PMID: 29326667
To identify carbohydrate-active enzymes (CAZymes) that might be particularly relevant for wood fiber processing, we performed a comparative metagenomic analysis of digestive systems from Canadian beaver () and North American...
10.
Quiroga Artigas G, Lapebie P, Leclere L, Takeda N, Deguchi R, Jekely G, et al.
Elife
. 2018 Jan;
7.
PMID: 29303477
Across the animal kingdom, environmental light cues are widely involved in regulating gamete release, but the molecular and cellular bases of the photoresponsive mechanisms are poorly understood. In hydrozoan jellyfish,...