Partha S Chowdhury
Overview
Explore the profile of Partha S Chowdhury including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
23
Citations
898
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Prabakaran P, Gupta A, Rao S, Rajpal D, Wendt M, Qiu Y, et al.
Commun Biol
. 2025 Jan;
8(1):133.
PMID: 39875530
Antibodies, essential components of adaptive immunity, derive their remarkable diversity primarily from V(D)J gene rearrangements, particularly within the heavy chain complementarity-determining region 3 (CDR-H3) where D genes play a major...
2.
Mahendra A, Haque A, Prabakaran P, Mackness B, Fuller T, Liu X, et al.
Commun Biol
. 2022 Oct;
5(1):1157.
PMID: 36310321
Immunization based antibody discovery is plagued by the paucity of antigen-specific B cells. Identifying these cells is akin to finding needle in a haystack. Current and emerging technologies while effective,...
3.
Zhang R, Prabakaran P, Yu X, Mackness B, Boudanova E, Hopke J, et al.
MAbs
. 2021 Apr;
13(1):1904546.
PMID: 33899674
Hybridoma technology has been valuable in the development of therapeutic antibodies. More recently, antigen-specific B-cell selection and display technologies are also gaining importance. A major limitation of these approaches used...
4.
Ramasubramanian A, Tennyson R, Magnay M, Kathuria S, Travaline T, Jain A, et al.
Antibodies (Basel)
. 2020 Nov;
9(4).
PMID: 33172091
Bispecific molecules are biologically significant, yet their complex structures pose important manufacturing and pharmacokinetic challenges. Nevertheless, owing to similarities with monoclonal antibodies (mAbs), IgG-like bispecifics conceptually align well with conventional...
5.
Prabakaran P, Chowdhury P
Cell Rep
. 2020 Jul;
31(13):107831.
PMID: 32610132
Human antibody repertoire data captured through next-generation sequencing (NGS) has enabled deeper insights into B cell immunogenetics and paratope diversity. By analyzing large public NGS datasets, we map the landscape...
6.
Kumar A, Chamoto K, Chowdhury P, Honjo T
Elife
. 2020 Mar;
9.
PMID: 32122466
PD-1 blockade therapy has revolutionized cancer treatments. However, a substantial population of patients is unresponsive. To rescue unresponsive patients, the mechanism of unresponsiveness to PD-1 blockade therapy must be elucidated....
7.
Rajan S, Kierny M, Mercer A, Wu J, Tovchigrechko A, Wu H, et al.
Commun Biol
. 2018 Oct;
1:5.
PMID: 30271892
The human antibody repertoire is increasingly being recognized as a valuable source of therapeutic grade antibodies. However, methods for mining primary antibody-expressing B cells are limited in their ability to...
8.
Chowdhury P, Chamoto K, Kumar A, Honjo T
Cancer Immunol Res
. 2018 Aug;
6(11):1375-1387.
PMID: 30143538
Although PD-1 blockade cancer immunotherapy has shown potential for a wide range of patients with cancer, its efficacy is limited, in part, due to the loss of effector cytotoxic T...
9.
Hemken P, Jeanblanc N, Rae T, Brophy S, Datwyler M, Xu Y, et al.
Pract Lab Med
. 2017 Nov;
9:58-68.
PMID: 29159257
Background: Dipeptidyl peptidase-4 (DPP-4) may be a suitable biomarker to identify people with severe asthma who have greater activation of the interleukin-13 (IL-13) pathway and may therefore benefit from IL-13-targeted...
10.
Xiao X, Douthwaite J, Chen Y, Kemp B, Kidd S, Percival-Alwyn J, et al.
MAbs
. 2017 Jun;
9(6):996-1006.
PMID: 28613102
Phage display antibody libraries are a rich resource for discovery of potential therapeutic antibodies. Single-chain variable fragment (scFv) libraries are the most common format due to the efficient display of...